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食管旁疝继发急性食管坏死

Acute Esophageal Necrosis Secondary to a Paraesophageal Hernia.

作者信息

Li Chris J, Claxton Benjamin B, Block Peter, Reilly Sean, Manski Scott, Choudhary Cuckoo

机构信息

Department of Internal Medicine, Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania, USA.

Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospitals, Philadelphia, Pennsylvania, USA.

出版信息

Case Rep Gastroenterol. 2021 Jul 5;15(2):594-597. doi: 10.1159/000517235. eCollection 2021 May-Aug.

Abstract

Acute esophageal necrosis (AEN) or "black esophagus" is a rare clinical entity caused by necrosis of distal esophageal mucosa stemming from esophageal ischemia. Possible etiologies are broad but most commonly include possible triggers of low-flow vascular states in the esophagus, including infections, broad-spectrum antibiotic use, and gastric volvulus, among others. Patients most commonly present clinically with acute onset hematemesis and melena. Here, we describe a patient who initially presented with multiple nonspecific gastrointestinal symptoms, including abdominal pain and nausea, that progressed over a 10-day period, culminating in multiple episodes of hematemesis prior to presentation. Endoscopic evaluation confirmed the diagnosis of AEN and unveiled a possible paraesophageal hernia (PEH) as the causative factor. A subsequent videofluoroscopic barium swallow was utilized to better characterize the upper gastrointestinal anatomy and confirmed the PEH as a likely etiology. Esophagogastroduodenoscopy (EGD) can often identify PEH independently, but in patients with AEN secondary to a possible, but unclear, PEH on EGD, a videofluoroscopic barium swallow is an appropriate and useful next step in confirming the diagnosis. While treatment of AEN traditionally involves fluid resuscitation, intravenous protein pump inhibitors, and total parenteral nutrition, surgical intervention is often indicated in patients who have a contributing and symptomatic PEH.

摘要

急性食管坏死(AEN)或“黑色食管”是一种罕见的临床病症,由食管缺血导致的远端食管黏膜坏死引起。可能的病因广泛,但最常见的包括食管低流量血管状态的可能诱因,如感染、广谱抗生素使用、胃扭转等。患者临床上最常表现为急性呕血和黑便。在此,我们描述一名患者,最初表现为多种非特异性胃肠道症状,包括腹痛和恶心,这些症状在10天内逐渐加重,最终在就诊前出现多次呕血。内镜评估确诊为AEN,并发现可能存在食管旁疝(PEH)作为致病因素。随后进行了视频荧光透视钡餐检查以更好地描绘上消化道解剖结构,并确认PEH可能是病因。食管胃十二指肠镜检查(EGD)通常可独立识别PEH,但对于EGD上可能存在但不明确的PEH继发AEN的患者,视频荧光透视钡餐检查是确认诊断的合适且有用的下一步检查。虽然AEN的传统治疗包括液体复苏、静脉注射质子泵抑制剂和全胃肠外营养,但对于有导致症状的PEH的患者,通常需要进行手术干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aed2/8454224/4b08274ec60b/crg-0015-0594-g01.jpg

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