Street Maria E, Sartori Chiara, Catellani Cecilia, Righi Beatrice
Division of Pediatric Endocrinology and Diabetology, Unit of Pediatrics, Department of Mother and Child, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
PhD Program in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Modena, Italy.
Front Pediatr. 2021 Sep 20;9:734899. doi: 10.3389/fped.2021.734899. eCollection 2021.
A significant increase in precocious puberty, rapidly progressive puberty and precocious menarche has been reported in Italy since the initial lockdown because of the pandemic, and this could represent a new emergency to be addressed during this pandemic. There is a need, therefore, for further understanding and research. Many causes could account for this. Initially, it was thought that the changes in life-style, in screen time, and sleeping habits could be the cause but if considered individually these are insufficient to explain this phenomenon. Likely, changes in central nervous mediators, and an increase in catecholamines could contribute as a trigger, however, these aspects are poorly studied and understood as well as the real perceptions of these children. Finally, staying more indoors has certainly exposed these children to specific contaminants working as endocrine disruptors which could also have had an effect. It would be of utmost importance to compare this phenomenon worldwide with appropriate studies in order to verify what is happening, and gain a new insight into the consequences of the covid-19 pandemic and into precocious puberty and for future prevention.
自意大利因疫情首次封锁以来，该国报告性早熟、快速进展性青春期和初潮过早的情况显著增加，这可能是此次疫情期间需要应对的一个新的紧急情况。因此，有必要进行进一步的了解和研究。这可能有多种原因。最初，人们认为生活方式、屏幕使用时间和睡眠习惯的改变可能是原因，但单独来看，这些不足以解释这一现象。中枢神经介质的变化以及儿茶酚胺的增加可能是触发因素，但这些方面以及这些孩子的真实感受都研究不足且了解甚少。最后，更多时间待在室内肯定使这些孩子接触到了作为内分泌干扰物的特定污染物，这也可能产生了影响。至关重要的是，通过适当的研究将全球范围内的这一现象进行比较，以核实正在发生的情况，并对新冠疫情的后果、性早熟以及未来的预防有新的认识。
