中青年男性临床冠心病与冠状动脉疾病的特征分析
Characteristic analysis of clinical coronary heart disease and coronary artery disease concerning young and middle-aged male patients.
作者信息
Peng Kai-Ge, Yu Hui-Lin
机构信息
Department of Cardiovascular Medicine, Anqing Municipal Hospital, Anqing 230032, Anhui Province, China.
出版信息
World J Clin Cases. 2021 Sep 6;9(25):7358-7364. doi: 10.12998/wjcc.v9.i25.7358.
BACKGROUND
Coronary heart disease (CHD) is a type of coronary atherosclerotic heart disease. In recent years, the incidence of CHD has been increasing annually, with an increasing number of young patients. Severe CHD may cause severe myocardial ischemia or myocardial necrosis, which in turn may cause myocardial infarction and related complications that seriously affect the life and health of the patient.
AIM
To examine the coronary arteries and clinical features of young and middle-aged male patients with CHD.
METHODS
From February 2019 to January 2020, 110 male CHD patients admitted to our hospital were selected as research subjects and were divided into two groups by age: middle-aged group ( = 55) and young group ( = 55). The coronary arteries and clinical features of the patients were compared.
RESULTS
There were no significant differences in dyslipidemia, stroke history, high-density lipoprotein cholesterol, or triacylglycerol ( > 0.05) between the two groups. In the young group, age, diabetes, hypertension, smoking history, body mass index, family history of CHD, drinking history, fibrinogen, low-density lipoprotein cholesterol, total cholesterol, and single-vessel disease were higher than those in the middle-aged group. Correspondingly, serum uric acid, hyperuricemia, myocardial infarction, Gensini score > 50, collateral circulation, multivessel disease, double vessel disease, involvement of the right coronary artery, and involvement of the left main coronary artery were lower in the young group than in the middle-aged group. The middle-aged group mainly suffered from a high Gensini score, implicating multiple arteries, whereas the young group was mainly affected by single-vessel disease. The between-group difference was significant ( < 0.05).
CONCLUSION
In CHD attacks, multiple coronary arteries are implicated in middle-aged male patients and single-vessel disease in young male patients.
背景
冠心病（CHD）是一种冠状动脉粥样硬化性心脏病。近年来，冠心病的发病率逐年上升，年轻患者数量不断增加。严重的冠心病可能导致严重的心肌缺血或心肌坏死，进而可能引发心肌梗死及相关并发症，严重影响患者的生命健康。
目的
研究中青年男性冠心病患者的冠状动脉情况及临床特征。
方法
选取2019年2月至2020年1月我院收治的110例男性冠心病患者作为研究对象，按年龄分为两组：中年组（≥55岁）和青年组（<55岁）。比较两组患者的冠状动脉情况及临床特征。
结果
两组患者在血脂异常、中风病史、高密度脂蛋白胆固醇或三酰甘油方面差异无统计学意义（P>0.05）。青年组患者的年龄、糖尿病、高血压、吸烟史、体重指数、冠心病家族史、饮酒史、纤维蛋白原、低密度脂蛋白胆固醇、总胆固醇及单支血管病变高于中年组。相应地，青年组患者的血清尿酸、高尿酸血症、心肌梗死、Gensini评分>50、侧支循环、多支血管病变、双支血管病变、右冠状动脉受累及左主冠状动脉受累低于中年组。中年组主要表现为Gensini评分高，累及多支动脉，而青年组主要为单支血管病变。组间差异有统计学意义（P<0.05）。
结论
在冠心病发作中，中年男性患者多累及多支冠状动脉，青年男性患者多为单支血管病变。
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