Tang Min, Wang Song-Hao, Li Hui-Lin, Chen Han, Sun Xin-Yi, Bian Wei-Wei, Sheng Jing, Ma Shao-Jun
Department of Geriatrics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
PeerJ. 2021 Feb 17;9:e10903. doi: 10.7717/peerj.10903. eCollection 2021.
Coronary heart disease (CHD) is the leading cause of morbidity and mortality among elderly individuals. Patients with CHD are at high risk for mental health disorders, and psychological issues may affect the quality of life (QoL) of these patients. Nevertheless, there is little evidence regarding the psychological issues and QoL of patients with CHD among the elderly population. This study aimed to investigate the relationship between comorbidities and mental status as well as QoL among elderly patients with CHD.
Overall, 216 patients were included in this cross-sectional, observational, single-center study. The demographics and clinical manifestations of the patients were collected from electronic medical records. All patients were interviewed using the Chinese version of Symptom Checklist 90 (SCL-90) to assess the mental health status and the World Health Organization Quality of Life-BREF questionnaire (WHOQOL-BREF) to assess the QoL.
In total, 96 men and 120 women, with a mean age of 71.69 ± 8.30 years, were included. When controlling for the patients' sex, marital status and stroke, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid type 2 diabetes mellitus had the significant influence on average positive factors (Coef., 5.809; 95% CI [2.467-9.152] = 0.001); when controlling for the patients' sex, marital status and type 2 diabetes mellitus, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid stroke had the significant influence on average positive factors (Coef., 8.680; 95% CI [4.826-12.534]; < 0.001); when controlling for the patients' sex, marital status, type 2 diabetes mellitus and stroke, multiple stepwise linear regression analyses suggested that for CHD patients, comorbid primary hypertension had the significant influence on phobic anxiety (Coef., 0.178; 95% CI [0.010-0.347]; = 0.038).
For elderly CHD patients, comorbid type 2 diabetes mellitus and stroke were at risk for psychological problems and lower QoL. Our findings may guide patients and clinicians to make better decisions and achieve better outcomes.
冠心病（CHD）是老年人发病和死亡的主要原因。冠心病患者患心理健康障碍的风险很高，心理问题可能会影响这些患者的生活质量（QoL）。然而，关于老年人群中冠心病患者的心理问题和生活质量的证据很少。本研究旨在调查老年冠心病患者的合并症与心理状态以及生活质量之间的关系。
总体而言，本横断面、观察性、单中心研究纳入了216例患者。患者的人口统计学和临床表现从电子病历中收集。所有患者均使用中文版症状自评量表90（SCL-90）进行访谈以评估心理健康状况，并使用世界卫生组织生活质量简表（WHOQOL-BREF）评估生活质量。
共纳入96名男性和120名女性，平均年龄为71.69±8.30岁。在控制患者的性别、婚姻状况和中风后，多元逐步线性回归分析表明，对于冠心病患者，合并2型糖尿病对平均阳性因子有显著影响（系数，5.809；95%可信区间[2.467-9.152]；P=0.001）；在控制患者的性别、婚姻状况和2型糖尿病后，多元逐步线性回归分析表明，对于冠心病患者，合并中风对平均阳性因子有显著影响（系数，8.680；95%可信区间[4.826-12.534]；P<0.001）；在控制患者的性别、婚姻状况、2型糖尿病和中风后，多元逐步线性回归分析表明，对于冠心病患者，合并原发性高血压对恐惧焦虑有显著影响（系数，0.178；95%可信区间[0.010-0.347]；P=0.038）。
对于老年冠心病患者，合并2型糖尿病和中风有心理问题和较低生活质量的风险。我们的研究结果可能会指导患者和临床医生做出更好的决策并取得更好的结果。
