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恶性血管外皮细胞瘤的化疗

Chemotherapy of malignant hemangiopericytoma.

作者信息

Wong P P, Yagoda A

出版信息

Cancer. 1978 Apr;41(4):1256-60. doi: 10.1002/1097-0142(197804)41:4<1256::aid-cncr2820410406>3.0.co;2-v.

DOI:10.1002/1097-0142(197804)41:4<1256::aid-cncr2820410406>3.0.co;2-v
PMID:346193
Abstract

Thirty-nine chemotherapy trials in 16 patients with metastatic hemangiopericytoma treated at MSKCC and 33 trials from the literature are reviewed. Adriamycin, alone or in combination drug regimens, is the most effective agent, producing complete and partial remission in 50% of cases. Other drugs which show some activity include vincristine, cyclophosphamide, actinomycin, methotrexate and DTIC. The available data indicate malignant hemangiopericytoma should be considered chemotherapeutically responsive tumors.

摘要

对16例在纪念斯隆凯特琳癌症中心接受治疗的转移性血管外皮细胞瘤患者进行的39项化疗试验以及文献中的33项试验进行了综述。阿霉素单独使用或与联合用药方案联合使用是最有效的药物,在50%的病例中产生完全缓解和部分缓解。其他显示出一定活性的药物包括长春新碱、环磷酰胺、放线菌素、甲氨蝶呤和达卡巴嗪。现有数据表明,恶性血管外皮细胞瘤应被视为对化疗有反应的肿瘤。

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1
Chemotherapy of malignant hemangiopericytoma.恶性血管外皮细胞瘤的化疗
Cancer. 1978 Apr;41(4):1256-60. doi: 10.1002/1097-0142(197804)41:4<1256::aid-cncr2820410406>3.0.co;2-v.
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Neuroblastoma in the adult: effective combination chemotherapy.成人神经母细胞瘤:有效的联合化疗
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Adriamycin versus methotrexate in five-drug combination chemotherapy for advanced breast cancer: a randomized trial.
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Chemotherapy of metastatic breast cancer in postmenopausal women: a controlled trial of cyclophosphamide versus a five-drug combination of cyclophosphamide, vincristine, methotrexate, 5-fluorouracil and prednisone.绝经后女性转移性乳腺癌的化疗:环磷酰胺与环磷酰胺、长春新碱、甲氨蝶呤、5-氟尿嘧啶和泼尼松五药联合方案的对照试验
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Combination chemotherapy in metastatic malignant melanoma: a randomized study of three DTIC-containing combination.转移性恶性黑色素瘤的联合化疗:三项含达卡巴嗪联合方案的随机研究
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A comparative clinical trial evaluating the combination of adriamycin, DTIC, and vincristine, the combination of actinomycin D, cyclophosphamide, and vincristine, and a single agent, methyl-CCNU, in advanced sarcomas.一项比较性临床试验,评估阿霉素、氮烯咪胺和长春新碱联合用药,放线菌素D、环磷酰胺和长春新碱联合用药,以及单一药物甲基环己亚硝脲治疗晚期肉瘤的效果。
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Treatment of advanced malignant hemangiopericytoma with combination adriamycin and DTIC: a report of four cases.阿霉素联合氮烯咪胺治疗晚期恶性血管外皮细胞瘤:4例报告
J Surg Oncol. 1983 Mar;22(3):167-70. doi: 10.1002/jso.2930220306.
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Combination chemotherapy with DTIC (NSC-45388) in advanced malignant melanoma, soft tissue sarcomas, and Hodgkin's disease.达卡巴嗪(NSC - 45388)联合化疗用于晚期恶性黑色素瘤、软组织肉瘤和霍奇金病。
Cancer Treat Rep. 1976 Feb;60(2):205-11.

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