Houssaint E, Hallet M M
J Leukoc Biol. 1986 Oct;40(4):469-77. doi: 10.1002/jlb.40.4.469.
The cell origin of the follicle-associated epithelium (FAE) of the bursa of Fabricius was studied by two different technical approaches. Precolonized quail bursal rudiments were grafted into chick embryos and the grafts were recovered 2 wk after hatching of the recipients. By taking advantage of the distinct nuclear characteristics of chick and quail cells, it could be shown that the specialized FAE consists of a mixture of epithelial cells, with special features, among which hemopoietic cells, originating from the host, are dispersed. Staining of chicken bursas with different monoclonal antibodies reacting either with the epithelial component (BEP-1) or with the hemopoietic cells of the bursa (L22, L17) confirmed that hemopoietic cells, presumably macrophages, are mixed with the epithelial cells at the level of FAE.
通过两种不同的技术方法研究了法氏囊滤泡相关上皮（FAE）的细胞起源。将预先定植的鹌鹑法氏囊原基移植到鸡胚中，并在受体孵化后2周回收移植体。利用鸡和鹌鹑细胞不同的核特征，可以表明特化的FAE由具有特殊特征的上皮细胞混合物组成，其中源自宿主的造血细胞分散在其中。用与上皮成分（BEP-1）或法氏囊造血细胞（L22、L17）反应的不同单克隆抗体对鸡法氏囊进行染色，证实造血细胞（可能是巨噬细胞）在FAE水平与上皮细胞混合。
