Janssen Pharmaceutica NV, Turnhoutseweg 30, 2340, Beerse, Belgium.
Janssen Research & Development, LLC, Titusville, NJ, USA.
J Autism Dev Disord. 2022 Oct;52(10):4219-4232. doi: 10.1007/s10803-021-05279-z. Epub 2021 Oct 8.
Individuals with autism spectrum disorder (ASD) have been found to view social scenes differently compared to typically developing (TD) peers, but results can vary depending on context and age. We used eye-tracking in children and adults (age 6-63) to assess allocation of visual attention in a dynamic social orientation paradigm previously used only in younger children. The ASD group (n = 94) looked less at the actor's face compared to TD (n = 38) when they were engaged in activity (mean percentage of looking time, ASD = 30.7% vs TD = 34.9%; Cohen's d = 0.56; p value < 0.03) or looking at a moving toy (24.5% vs 33.2%; d = 0.65; p value < 0.001). Findings indicate that there are qualitative differences in allocation of visual attention to social stimuli across ages in ASD.ClinicalTrials.gov identifier: NCT02668991.
自闭症谱系障碍（ASD）个体与典型发育（TD）同龄人相比，被发现对社交场景的看法不同，但结果可能因背景和年龄而异。我们使用眼动追踪技术在儿童和成人（6-63 岁）中评估了先前仅在年幼儿童中使用的动态社交定向范式中视觉注意力的分配。与 TD（n=38）相比，当 ASD 组（n=94）参与活动（注视时间的平均百分比，ASD=30.7% vs TD=34.9%；Cohen's d=0.56；p 值<0.03）或观察移动玩具时，他们较少注视演员的脸（24.5% 对 33.2%；d=0.65；p 值<0.001）。研究结果表明，在 ASD 中，跨年龄段对社交刺激的视觉注意力分配存在定性差异。ClinicalTrials.gov 标识符：NCT02668991。
