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1950 - 1951年至1981 - 1982年美国与瑞典肺癌的时间变化比较

Comparison of temporal changes in U.S. and Swedish lung cancer, 1950-51 to 1981-82.

作者信息

Manton K G, Malker H, Malker B

出版信息

J Natl Cancer Inst. 1986 Sep;77(3):665-75. doi: 10.1093/jnci/77.3.665.

Abstract

A comparison was made of temporal changes in lung cancer risk for the U.S. white and Swedish populations from 1950-51 to 1981-82 with the use of both life-table- and cohort-specific proportional hazard models to illustrate different features of the time series. Marked differences were noted for the two populations; Swedish lung cancer risks were generally lower than those in the United States. Sex-specific analyses were conducted that showed that Swedish males had a mortality rate roughly half that for U.S. males over the entire period. In contrast, U.S. white female mortality rates, though roughly equal to those for Swedish females in 1950-51, experienced a relatively more rapid increase; their rates were double the Swedish rates by 1980. The factors contributing to these patterns, such as marked cohort differences in risk, are identified by the various stages of analysis.

摘要

利用寿命表特定队列比例风险模型,对1950 - 1951年至1981 - 1982年期间美国白人和瑞典人群肺癌风险的时间变化进行了比较,以阐明时间序列的不同特征。注意到这两个人群存在显著差异;瑞典的肺癌风险总体低于美国。进行了按性别分析,结果显示在整个时期内,瑞典男性的死亡率约为美国男性的一半。相比之下,美国白人女性的死亡率虽然在1950 - 1951年时与瑞典女性大致相当,但增长相对较快;到1980年,她们的死亡率是瑞典女性的两倍。通过各个分析阶段确定了导致这些模式的因素,如风险方面明显的队列差异。

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