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第二代南亚裔美国人的心血管健康和亚临床动脉粥样硬化:MASALA 研究。

Cardiovascular health and subclinical atherosclerosis in second generation South Asian Americans: The MASALA study.

机构信息

Division of Cardiology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Indian Heart J. 2021 Sep-Oct;73(5):629-632. doi: 10.1016/j.ihj.2021.07.010. Epub 2021 Jul 29.

DOI:10.1016/j.ihj.2021.07.010
PMID:34627581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8514401/
Abstract

We describe cardiovascular health (CVH) in second-generation (U.S.-born) South Asian Americans in the MASALA study, a population for whom CVH is not previously described. CVH factors in second-generation (N = 21) compared with first-generation (N = 495) South Asian Americans included: total cholesterol (199 ± 31 versus 191 ± 35 mg/dL, p = 0.25), low-density lipoprotein cholesterol (121 ± 27 versus 115 ± 30 mg/dL, p = 0.41), triglycerides (163 ± 197 versus 138 ± 72 mg/dL, p = 0.10), diet score (66 ± 8 versus 70 ± 6 points, p = 0.06), BMI (27.6 ± 4.9 versus 26.2 ± 4.1 kg/m, p = 0.12), and CAC prevalence (26.3% versus 23.9%, p = 0.34). Age- and sex-adjusted differences were not statistically significant. Further investigation of CVH in this risk-enhanced population may help identify differences between second-generation and first-generation immigrant South Asians in the U.S.

摘要

我们在 MASALA 研究中描述了第二代(美国出生)南亚裔美国人的心血管健康 (CVH),这是一个以前没有描述过 CVH 的人群。与第一代南亚裔美国人(N=495)相比,第二代南亚裔美国人(N=21)的 CVH 因素包括:总胆固醇(199±31 与 191±35mg/dL,p=0.25)、低密度脂蛋白胆固醇(121±27 与 115±30mg/dL,p=0.41)、甘油三酯(163±197 与 138±72mg/dL,p=0.10)、饮食评分(66±8 与 70±6 分,p=0.06)、BMI(27.6±4.9 与 26.2±4.1kg/m,p=0.12)和 CAC 患病率(26.3%与 23.9%,p=0.34)。年龄和性别调整后的差异没有统计学意义。进一步研究这种风险增强人群的 CVH 可能有助于确定美国第二代和第一代移民南亚裔之间的差异。

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