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噪声性听力损失的抗氧化治疗与预防研究进展

[Research progress on antioxidant therapy and prevention in noise- induced hearing loss].

作者信息

Gu Xiaona, Dai Yanhong, She Modong

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Sep;35(9):850-853. doi: 10.13201/j.issn.2096-7993.2021.09.019.

Abstract

Noise- induced hearing loss usually refers to auditory impairment which is caused by long-term exposure to noise. The occupational noise problem is serious and urgently needs to be addressed, along with the lack of effective treatments. Recent studies have shown that the imbalance between oxidation and antioxidation is the source of the disease. To correct the redox reaction imbalance and to maintain an equilibrium of the redox reaction have always been the research focus of the prevention and treatment in noise induced hearing loss. This article reviews antioxidant therapy and prevention in noise induced hearing loss, including antioxidants, antioxidant enzymes and herbal medicine.

摘要

噪声性听力损失通常是指因长期暴露于噪声环境而导致的听觉损伤。职业噪声问题严重,且迫切需要解决,同时还缺乏有效的治疗方法。最近的研究表明,氧化与抗氧化之间的失衡是该病的根源。纠正氧化还原反应失衡并维持氧化还原反应的平衡一直是噪声性听力损失防治研究的重点。本文综述了噪声性听力损失的抗氧化治疗与预防,包括抗氧化剂、抗氧化酶和草药。

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[Research progress on antioxidant therapy and prevention in noise- induced hearing loss].噪声性听力损失的抗氧化治疗与预防研究进展
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本文引用的文献

1
Antioxidative stress-induced damage in cochlear explants.抗氧化应激诱导的耳蜗外植体损伤。
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Local Drug Delivery for Prevention of Hearing Loss.用于预防听力损失的局部药物递送
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