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Local Drug Delivery for Prevention of Hearing Loss.用于预防听力损失的局部药物递送
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Effects of D-methionine in mice with noise-induced hearing loss mice.D-蛋氨酸对噪声性听力损失小鼠的影响。
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Avenanthramide-C prevents noise- and drug-induced hearing loss while protecting auditory hair cells from oxidative stress.芹黄素-C可预防噪音和药物引起的听力损失，同时保护听觉毛细胞免受氧化应激的影响。
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Mitochondria-Targeted Antioxidants for Treatment of Hearing Loss: A Systematic Review.用于治疗听力损失的线粒体靶向抗氧化剂：一项系统评价
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Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage.佩贾金介导的pexophagy 可保护听觉毛细胞免受噪声损伤。
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Protective Effects of N-Acetyl-L-Cysteine on the Density of Spiral Ganglion Cells and Histological Changes Induced by Continuous Noise Exposure in Rats.N-乙酰-L-半胱氨酸对大鼠持续噪声暴露所致螺旋神经节细胞密度及组织学变化的保护作用
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噪声性听力损失的抗氧化治疗与预防研究进展

[Research progress on antioxidant therapy and prevention in noise- induced hearing loss].

作者信息

Gu Xiaona, Dai Yanhong, She Modong

出版信息

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2021 Sep;35(9):850-853. doi: 10.13201/j.issn.2096-7993.2021.09.019.

DOI:10.13201/j.issn.2096-7993.2021.09.019
PMID:34628844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10127829/
Abstract

Noise- induced hearing loss usually refers to auditory impairment which is caused by long-term exposure to noise. The occupational noise problem is serious and urgently needs to be addressed, along with the lack of effective treatments. Recent studies have shown that the imbalance between oxidation and antioxidation is the source of the disease. To correct the redox reaction imbalance and to maintain an equilibrium of the redox reaction have always been the research focus of the prevention and treatment in noise induced hearing loss. This article reviews antioxidant therapy and prevention in noise induced hearing loss, including antioxidants, antioxidant enzymes and herbal medicine.

摘要

噪声性听力损失通常是指因长期暴露于噪声环境而导致的听觉损伤。职业噪声问题严重，且迫切需要解决，同时还缺乏有效的治疗方法。最近的研究表明，氧化与抗氧化之间的失衡是该病的根源。纠正氧化还原反应失衡并维持氧化还原反应的平衡一直是噪声性听力损失防治研究的重点。本文综述了噪声性听力损失的抗氧化治疗与预防，包括抗氧化剂、抗氧化酶和草药。