Sima Romina-Marina, Pleş Liana, Socea Bogdan, Sklavounos Panagiotis, Negoi Ionuţ, Stănescu Anca-Daniela, Iordache Ioan-Iulian, Hamoud Bashar Haj, Radosa Marc Phillip, Juhasz-Boess Ingolf, Solomayer Erich Franz, Dimitriu Mihai C T, Cîrstoveanu Cătălin, Şerban Dragoş, Radosa Julia Caroline
Department of Obstetrics and Gynecology, 'Carol Davila' University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of Obstetrics and Gynecology, 'Sf. Ioan' Hospital, Bucur Maternity, 040294 Bucharest, Romania.
Exp Ther Med. 2021 Nov;22(5):1283. doi: 10.3892/etm.2021.10718. Epub 2021 Sep 13.
Endometriosis has a negative influence on the physical, psychological, and social aspects of a patient's life; therefore, it affects the health-related quality of life (HRQoL). The current review aimed to investigate the efficiency of a 36-item generic questionnaire survey (SF-36) for patients with endometriosis who were undergoing medical or surgical treatment. A search strategy including the key words 'endometriosis', 'quality of life' (QOL), and 'questionnaire SF-36' was applied using the PubMed/MEDLINE, EMBASE, and Cochrane databases in order to include articles that evaluated the QOL among women with endometriosis using the SF-36. Only articles that included interviews of patients both before and after surgical or medical endometriosis treatment or those articles that compared study groups were considered. The qualitative analysis was based on 37 articles, whereas the quantitative analysis utilized 14 articles. The research participants included 11,101 women, among whom 6,888 patients were diagnosed with endometriosis. The analysis recorded 17 studies dealing with all types of endometriosis, 9 studies dealing with deep infiltrative endometriosis (DIE), and 9 studies dealing with bowel endometriosis or DIE with bowel involvement. QOL was evaluated using only SF-36 in 12 studies that collectively included 1,912 women and using SF-36 in association with other questionnaires in 25 studies that collectively included 8,022 women. For patients with endometriosis, physical functioning [odds ratio (OR), 78.87; 95% confidence interval (CI), 68.97-88.77; I=98.77%; P≤0.001] was the most affected life parameter. This parameter showed the highest improvement after surgical intervention (OR, 63.39; 95% CI, 48.71-78.07; I=97.65%; P≤0.001) or hormonal treatment (OR, 38.65; 95% CI, 14.39-62.91; I=38.65%; P≤0.001). The 36-item survey generic questionnaire seems to be an efficient tool for assessment of the QOL of life of women with endometriosis who are undergoing surgical or medical treatment. It can be applied before and after the procedure, and it can also be used for comparing study groups.
子宫内膜异位症对患者生活的身体、心理和社会方面都有负面影响；因此，它会影响与健康相关的生活质量（HRQoL）。本综述旨在调查一份包含36个条目的通用问卷调查（SF-36）对正在接受药物或手术治疗的子宫内膜异位症患者的有效性。采用搜索策略，在PubMed/MEDLINE、EMBASE和Cochrane数据库中使用关键词“子宫内膜异位症”、“生活质量”（QOL）和“问卷SF-36”，以便纳入使用SF-36评估子宫内膜异位症女性生活质量的文章。仅考虑那些包括手术或药物治疗子宫内膜异位症前后患者访谈的文章，或那些比较研究组的文章。定性分析基于37篇文章，而定量分析使用了14篇文章。研究参与者包括11101名女性，其中6888名患者被诊断为子宫内膜异位症。分析记录了17项涉及所有类型子宫内膜异位症的研究、9项涉及深部浸润性子宫内膜异位症（DIE）的研究以及9项涉及肠道子宫内膜异位症或伴有肠道受累的DIE的研究。12项研究仅使用SF-36评估生活质量，这些研究共纳入1912名女性；25项研究将SF-36与其他问卷结合使用，这些研究共纳入8022名女性。对于子宫内膜异位症患者，身体功能[比值比（OR），78.87；95%置信区间（CI），68.97 - 88.77；I = 98.77%；P≤0.001]是受影响最大的生活参数。该参数在手术干预（OR，63.39；95% CI，48.71 - 待补充完整后继续翻译78.07；I = 97.65%；P≤0.001）或激素治疗（OR，38.65；95% CI，14.39 - 62.91；I = 38.65%；P≤0.001）后改善最为明显。这份包含36个条目的通用调查问卷似乎是评估正在接受手术或药物治疗的子宫内膜异位症女性生活质量的有效工具。它可在治疗前后应用，也可用于比较研究组。
