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透析期间有低血压和无低血压患者的超声心动图参数。

Echocardiographic parameters in patients with and without hypotension during dialysis.

作者信息

Poorzand Hoorak, Sharifipour Farzaneh, Kerachian Abdollah, Ghaderi Fereshteh, Alimi Hedieh, Bigdelu Leila, Fazlinejad Afsoon, Morovatdar Negar, Ataei Banafsheh

机构信息

Vascular and Endovascular Surgery Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Kidney Transplantation Research Center, Department of Internal Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Cardiovasc Thorac Res. 2021;13(3):228-233. doi: 10.34172/jcvtr.2021.41. Epub 2021 Aug 25.

Abstract

Hypotension during dialysis is a common complication of hemodialysis and is associated with increased patient mortality and morbidity. Intradialytic hypotension is a decrease in systolic BP ≥20 mm Hg or a reduction in mean arterial pressure by 10 mm Hg along with clinical events and the need for correction. This study compares cardiac function, using transthoracic echocardiography with strain modality in patients with intradialytic hypotension with those without hypotension during dialysis. We studied 60 patients with chronic renal failure undergoing regular hemodialysis from April 2018 to February 2019. We compared thirty patients in the intradialytic hypotension group, with the remaining 30 patients in the control group. We did transthoracic echocardiography a day after hemodialysis using conventional, tissue doppler, and strain imaging. Early diastolic mitral annulus velocity (e') was lower in the intradialytic hypotension group in comparison with the control group which their difference was statistically significant (5.540 ± 1.51 versus 6.920 ± 1.98, value:0.007) Left Ventricular Ejection Fraction (LVEF) was also significantly lower in the intradialytic hypotension group (51.07 ± 8.714 versus 59.43 ± 4.133, value < 0.001). Global Longitudinal Strain (GLS) was significantly lower in the intradialytic hypotension group (-14.17 ± 2.79 versus -18.99 ± 2.25, value < 0.001). The receiver operator characteristics (ROC) curve point-coordinates that GLS of -16.85 and lower (more positive) has 83% sensitivity and 87% specificity for intradialytic hypotension. The echocardiographic assessment could be used as a tool for the prediction of hypotension during dialysis.

摘要

透析期间低血压是血液透析的常见并发症,与患者死亡率和发病率增加相关。透析期间低血压是指收缩压下降≥20mmHg或平均动脉压降低10mmHg,同时伴有临床症状且需要纠正。本研究采用经胸超声心动图应变模式,比较透析期间发生低血压的患者与未发生低血压的患者的心脏功能。我们研究了2018年4月至2019年2月期间60例接受定期血液透析的慢性肾衰竭患者。我们将30例透析期间低血压组患者与其余30例对照组患者进行比较。在血液透析后一天,我们使用传统、组织多普勒和应变成像进行经胸超声心动图检查。与对照组相比,透析期间低血压组患者二尖瓣环舒张早期速度(e')较低,差异有统计学意义(5.540±1.51对6.920±1.98,P值:0.007)。透析期间低血压组患者的左心室射血分数(LVEF)也显著较低(51.07±8.714对59.43±4.133,P值<0.001)。透析期间低血压组患者的整体纵向应变(GLS)显著较低(-14.17±2.79对-18.99±2.25,P值<0.001)。受试者工作特征(ROC)曲线的点坐标显示,GLS为-16.85及更低(更正)时,对透析期间低血压的敏感性为83%,特异性为87%。超声心动图评估可作为预测透析期间低血压的一种工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/694a/8493227/fe50f2eff2d8/jcvtr-13-228-g001.jpg

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