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Serological response to the BNT162b2 mRNA or ChAdOx1 nCoV-19 COVID-19 vaccine after first and second doses in patients with plasma cell disorders: influence of host and disease factors.

作者信息

Chan Wei Yee, Howells Lara, Wilson William, Sanchez Emilie, Ainley Louise, Chavda Selina J, Dowling Emma, Correia Nuno, Lecat Catherine S Y, McMillan Annabel, Wisniowski Brendan, Mahmood Shameem, Papanikolaou Xenofon, Lee Lydia, Sive Jonathan, Kyriakou Charalampia, Wechalekar Ashutosh, Popat Rakesh, Rabin Neil, Nastouli Eleni, Yong Kwee L, Xu Ke

机构信息

Department of Haematology, University College London Hospitals NHS Foundation Trust, London, UK.

Research Department of Haematology, UCL Cancer Institute, London, UK.

出版信息

Br J Haematol. 2022 Feb;196(3):e21-e26. doi: 10.1111/bjh.17864. Epub 2021 Oct 10.

DOI:10.1111/bjh.17864
PMID:34632575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8652995/
Abstract
摘要

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本文引用的文献

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Immun Ageing. 2021 Aug 20;18(1):34. doi: 10.1186/s12979-021-00246-9.
2
Autoantibodies neutralizing type I IFNs are present in 4% of uninfected individuals over 70 years old and account for 20% of COVID-19 deaths.在 70 岁以上未感染的人群中,有 4%存在中和 I 型干扰素的自身抗体,占 COVID-19 死亡人数的 20%。
Sci Immunol. 2021 Aug 19;6(62). doi: 10.1126/sciimmunol.abl4340.
3
Development of antibody response to SARS-CoV-2 following asymptomatic infection in patients with plasma cell disorders on immunomodulatory therapy.接受免疫调节治疗的浆细胞疾病患者无症状感染新型冠状病毒2后抗体反应的发展情况。
Br J Haematol. 2021 Sep;194(5):857-861. doi: 10.1111/bjh.17441. Epub 2021 Jul 29.
4
Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant.Covid-19 疫苗对 B.1.617.2(德尔塔)变异株的有效性。
N Engl J Med. 2021 Aug 12;385(7):585-594. doi: 10.1056/NEJMoa2108891. Epub 2021 Jul 21.
5
Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma.多发性骨髓瘤患者对两剂新冠病毒RNA疫苗的严重急性呼吸综合征冠状病毒2刺突抗体反应高度可变。
Cancer Cell. 2021 Aug 9;39(8):1028-1030. doi: 10.1016/j.ccell.2021.06.014. Epub 2021 Jun 29.
6
Humoral response rate and predictors of response to BNT162b2 mRNA COVID19 vaccine in patients with multiple myeloma.多发性骨髓瘤患者对 BNT162b2 mRNA COVID19 疫苗的体液反应率和反应预测因子。
Br J Haematol. 2021 Oct;195(2):186-193. doi: 10.1111/bjh.17608. Epub 2021 Jul 1.
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Lancet Oncol. 2021 Jun;22(6):765-778. doi: 10.1016/S1470-2045(21)00213-8. Epub 2021 Apr 27.
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Response to first vaccination against SARS-CoV-2 in patients with multiple myeloma.多发性骨髓瘤患者对严重急性呼吸综合征冠状病毒2首次疫苗接种的反应。
Lancet Haematol. 2021 Jun;8(6):e389-e392. doi: 10.1016/S2352-3026(21)00110-1. Epub 2021 Apr 19.
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Low neutralizing antibody responses against SARS-CoV-2 in older patients with myeloma after the first BNT162b2 vaccine dose.骨髓瘤老年患者在接种第一剂BNT162b2疫苗后对新冠病毒的中和抗体反应较低。
Blood. 2021 Jul 1;137(26):3674-3676. doi: 10.1182/blood.2021011904.