Department of Radiation Convergence Engineering, Yonsei University, Wonju, Korea.
Department of Nuclear Engineering, Hanyang University, Seoul, Korea.
J Appl Clin Med Phys. 2022 Jan;23(1):e13448. doi: 10.1002/acm2.13448. Epub 2021 Oct 11.
Tetrahedral mesh (TM)-based computational human phantoms have recently been developed for evaluation of exposure dose with the merit of precisely representing human anatomy and the changing posture freely. However, conversion of recently developed TM phantoms to the Digital Imaging and Communications in Medicine (DICOM) file format, which can be utilized in the clinic, has not been attempted. The aim of this study was to develop a technique, called TET2DICOM, to convert the TM phantoms to DICOM datasets for accurate treatment planning.
The TM phantoms were sampled in voxel form to generate the DICOM computed tomography images. The DICOM-radiotherapy structure was defined based on the contour data. To evaluate TET2DICOM, the shape distortion of the TM phantoms during the conversion process was assessed, and the converted DICOM dataset was implemented in a commercial treatment planning system (TPS).
The volume difference between the TM phantoms and the converted DICOM dataset was evaluated as less than about 0.1% in each organ. Subsequently, the converted DICOM dataset was successfully implemented in MIM (MIM Software Inc., Cleveland, USA, version 6.5.6) and RayStation (RaySearch Laboratories, Stockholm, Sweden, version 5.0). Additionally, the various possibilities of clinical application of the program were confirmed using a deformed TM phantom in various postures.
In conclusion, the TM phantom, currently the most advanced computational phantom, can be implemented in a commercial TPS and this technique can enable various TM-based applications, such as evaluation of secondary cancer risk in radiotherapy.
基于四面体网格(TM)的计算人体模型最近已被开发出来,用于评估暴露剂量,其优点是能够精确地表示人体解剖结构和自由改变姿势。然而,最近开发的 TM 体模尚未尝试转换为可在临床中使用的数字成像和通信医学(DICOM)文件格式。本研究的目的是开发一种名为 TET2DICOM 的技术,将 TM 体模转换为 DICOM 数据集,以进行精确的治疗计划。
TM 体模以体素形式进行采样,以生成 DICOM 计算机断层扫描图像。根据轮廓数据定义 DICOM-放射治疗结构。为了评估 TET2DICOM,评估了 TM 体模在转换过程中的形状失真,并在商业治疗计划系统(TPS)中实施了转换后的 DICOM 数据集。
在每个器官中,TM 体模和转换后的 DICOM 数据集之间的体积差异评估小于约 0.1%。随后,转换后的 DICOM 数据集成功地在 MIM(美国克利夫兰的 MIM 软件公司,版本 6.5.6)和 RayStation(瑞典斯德哥尔摩的 RaySearch Laboratories,版本 5.0)中实施。此外,使用各种姿势下的变形 TM 体模,确认了该程序在各种临床应用中的各种可能性。
总之,目前最先进的计算体模 TM 体模可以在商业 TPS 中实施,该技术可以实现各种基于 TM 的应用,如放射治疗中继发性癌症风险的评估。