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心脏重症监护病房从开放式人员配备模式向封闭式人员配备模式的转变改善了临床结局。

Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes.

机构信息

Section of Cardiovascular Medicine Yale School of Medicine New Haven CT.

Yale National Clinicians Scholar Program New Haven CT.

出版信息

J Am Heart Assoc. 2021 Feb 2;10(3):e018182. doi: 10.1161/JAHA.120.018182. Epub 2021 Jan 8.

Abstract

Background Several studies have shown improved outcomes in closed compared with open medical and surgical intensive care units. However, very little is known about the ideal organizational structure in the modern cardiac intensive care unit (CICU). Methods and Results We retrospectively reviewed consecutive unique admissions (n=3996) to our tertiary care CICU from September 2013 to October 2017. The aim of our study was to assess for differences in clinical outcomes between an open compared with a closed CICU. We used multivariable logistic regression adjusting for demographics, comorbidities, and severity of illness. The primary outcome was in-hospital mortality. We identified 2226 patients in the open unit and 1770 in the closed CICU. The unadjusted in-hospital mortality in the open compared with closed unit was 9.6% and 8.9%, respectively (=0.42). After multivariable adjustment, admission to the closed unit was associated with a lower in-hospital mortality (odds ratio [OR], 0.69; 95% CI: 0.53-0.90, =0.007) and CICU mortality (OR, 0.70; 95% CI, 0.52-0.94, =0.02). In subgroup analysis, admissions for cardiac arrest (OR, 0.42; 95% CI, 0.20-0.88, =0.02) and respiratory insufficiency (OR, 0.43; 95% CI, 0.22-0.82, =0.01) were also associated with a lower in-hospital mortality in the closed unit. We did not find a difference in CICU length of stay or total hospital charges (>0.05). Conclusions We found an association between lower in-hospital and CICU mortality after the transition to a closed CICU. These results may help guide the ongoing redesign in other tertiary care CICUs.

摘要

背景

多项研究表明,与开放式医疗和外科重症监护病房相比,封闭式重症监护病房的治疗效果更好。然而,对于现代心脏重症监护病房(CICU)的理想组织结构,我们知之甚少。

方法和结果

我们回顾性分析了 2013 年 9 月至 2017 年 10 月期间我院三级心脏重症监护病房的连续住院患者(n=3996)。本研究的目的是评估与开放式心脏重症监护病房相比,封闭式心脏重症监护病房在临床结局方面的差异。我们使用多变量逻辑回归调整了人口统计学、合并症和疾病严重程度。主要结局是住院期间死亡率。我们发现开放式单元中有 2226 例患者,封闭式单元中有 1770 例患者。开放式单元和封闭式单元的未调整住院死亡率分别为 9.6%和 8.9%(=0.42)。经过多变量调整后,与入住开放式单元相比,入住封闭式单元与较低的住院死亡率(比值比[OR],0.69;95%置信区间[CI]:0.53-0.90,=0.007)和 CICU 死亡率(OR,0.70;95% CI,0.52-0.94,=0.02)相关。亚组分析显示,心脏骤停(OR,0.42;95% CI,0.20-0.88,=0.02)和呼吸功能不全(OR,0.43;95% CI,0.22-0.82,=0.01)患者的住院死亡率也较低。我们未发现 CICU 住院时间或总住院费用(>0.05)的差异。

结论

我们发现从开放式 CICU 过渡到封闭式 CICU 后,住院和 CICU 死亡率降低。这些结果可能有助于指导其他三级心脏 CICU 的持续重新设计。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/048c/7955420/a1706ae338bc/JAH3-10-e018182-g001.jpg

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