Grześ A, Szamatowicz M
Endokrinologie. 1978 Feb;71(1):40-4.
Estimations of immunoreactive LH-RH and LH in pooled sera of girls, adult women and postmenopausal women have been carried out. The girls were divided into three groups: I--girls aged 2--4 years, II--girls aged 5--8 years and III--girls 9--12 years of age. The estimated concentrations of LH-RH in particular groups were as following: in group I--1.2 +/- 0.2 pg/ml, in group II--2.2 +/- 0.4 pg/ml, in group III 31.0 +/- 4.4 pg/ml, in adult women 6.3 +/- 1.8 pg/ml. and in postmenopausal women 16.6 +/- 2.4 pg/ml. The concentrations of LH in the same groups were 4.3 +/- 0.7; 4.5 +/- 0.8; 11.0 +/- 1.4, 23.3 +/- 2.4; and 120.0 +/- 14.7 mIU/ml, respectively. The authors suggest that the sexual maturation of girls is initiated by the enhanced hypothalamic activity, reflected in higher concentrations of immunoreactive LH-RH in peripheral serum.
已对女童、成年女性和绝经后女性混合血清中的免疫反应性促黄体生成激素释放激素（LH - RH）和促黄体生成素（LH）进行了测定。女童被分为三组：第一组——2至4岁的女童，第二组——5至8岁的女童，第三组——9至12岁的女童。特定组中LH - RH的估计浓度如下：第一组为1.2±0.2皮克/毫升，第二组为2.2±0.4皮克/毫升，第三组为31.0±4.4皮克/毫升，成年女性为6.3±1.8皮克/毫升，绝经后女性为16.6±2.4皮克/毫升。相同组中LH的浓度分别为4.3±0.7；4.5±0.8；11.0±1.4；23.3±2.4；和120.0±14.7毫国际单位/毫升。作者认为，女童的性成熟是由下丘脑活动增强引发的，这在外周血清中免疫反应性LH - RH浓度升高上有所体现。
