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泰国通过分子分析确诊眼部犬恶丝虫病病例由犬恶丝虫引起。

Ocular Dirofilariasis Case in Thailand Confirmed by Molecular Analysis to Be Caused by Dirofilaria immitis.

机构信息

Department of Ophthalmology, Chumphae Hospital, Khon Kaen, Thailand.

Department of Parasitology and Excellence in Medical Innovation, and Technology Research Group, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

Am J Trop Med Hyg. 2021 Oct 11;106(1):204-207. doi: 10.4269/ajtmh.21-0764.

Abstract

A rare ocular dirofilariasis case along with the clinical characteristics, treatment, and outcome is reported. A whitish roundworm (10.6 cm long and 0.5 mm width) emerged from the pterygium, a triangular tissue growth on the cornea of the eye, of a male patient. The worm had a rounded anterior part, mouth without lips, smooth cuticular surface, and short rounded posterior tail with spicules: these features suggested that it was a male Dirofilaria sp. Molecular identification confirmed that the worm belonged to Dirofilaria immitis. This is the first molecular confirmation that D. immitis is a causative agent of ocular dirofilariasis in Thailand: dirofilariasis is a newly emerging zoonotic disease. Physicians should be alert to zoonotic filarial worms and knowledgeable about treatment of this disease.

摘要

报告了 1 例罕见眼部犬恶丝虫病病例,包括其临床特征、治疗和结局。1 条白色的圆形线虫(长 10.6 厘米,宽 0.5 毫米)从男性患者的翼状胬肉(眼角的三角形组织生长物)中冒出。该虫体具有圆形的前部、无唇的口、光滑的表皮表面和短而圆形的带刺的后部尾巴:这些特征表明它是雄性犬恶丝虫。分子鉴定证实该虫属于犬恶丝虫。这是首次分子确认犬恶丝虫是导致泰国眼部犬恶丝虫病的病原体:犬恶丝虫病是一种新出现的人畜共患寄生虫病。医生应警惕人畜共患的丝虫,并了解该疾病的治疗方法。

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