School of Psychology, The University of Queensland, Brisbane, Queensland, Australia
National Centre for Youth Substance Use Research, The University of Queensland, Brisbane, Queensland, Australia.
BMJ Open. 2021 Oct 11;11(10):e045607. doi: 10.1136/bmjopen-2020-045607.
Transdiagnostic cognitive-behavioural therapy (CBT) targets common psychological factors that underlie multiple disorders. While transdiagnostic interventions are a promising new approach, limited research has evaluated these treatments within the alcohol and other drug (AOD) sector for young people with comorbid mental health symptoms. This project will examine the feasibility and preliminary efficacy of FullFix-a new risk-targeted transdiagnostic CBT telehealth programme for comorbid AOD and depression/anxiety disorders in young people. Secondary aims are to identify moderators and mediators of treatment outcomes, to determine how and why treatment is effective and who is most likely to benefit.
METHODS/DESIGN: Participants will be 130 young people (aged 16-35) accessing AOD services in Queensland, Australia, with comorbid mental health symptoms. They will be randomised to receive either the FullFix intervention plus standard AOD care or standard AOD care alone. Primary outcomes on AOD use and mental health symptoms will be reassessed at 6 weeks, 3 months, 6 months and 12 months, along with secondary outcomes of emotion regulation, social connectedness, perceived self-efficacy, coping skills and quality of life. The trial commenced on October 2018 and expected completion date is September 2021.
Ethical approval for this trial was provided by the University of Queensland (#2018001185). The results of the trial will be disseminated through publication in a peer-reviewed scientific journal, scientific presentations at conferences and distributed via a report and presentations to the partner organisation.
ACTRN12618001563257.
跨诊断认知行为疗法（CBT）针对的是多种障碍所共有的常见心理因素。虽然跨诊断干预是一种很有前途的新方法，但在酒精和其他药物（AOD）领域，针对有共病心理健康症状的年轻人，对这些治疗方法的研究有限。本项目将评估 FullFix-一种针对 AOD 和抑郁/焦虑障碍共病的新风险靶向跨诊断 CBT 远程治疗方案在年轻人中的可行性和初步疗效。次要目标是确定治疗结果的调节因素和中介因素，以确定治疗的效果如何以及为何有效，以及谁最有可能受益。
方法/设计：参与者将是 130 名在澳大利亚昆士兰州接受 AOD 服务且有共病心理健康症状的年轻人（年龄 16-35 岁）。他们将被随机分配接受 FullFix 干预加标准 AOD 护理或标准 AOD 护理。将在 6 周、3 个月、6 个月和 12 个月时重新评估 AOD 使用和心理健康症状的主要结果，以及情绪调节、社会联系、感知自我效能、应对技能和生活质量的次要结果。该试验于 2018 年 10 月开始，预计完成日期为 2021 年 9 月。
该试验的伦理批准由昆士兰大学提供（#2018001185）。试验结果将通过在同行评议的科学期刊上发表、在会议上进行科学报告以及通过报告和报告向合作伙伴组织分发来传播。
ACTRN12618001563257。
