Department of General Surgery, Tianjin Union Medical Centre, Tianjin, China.
Department of Pathology, Tianjin Union Medical Centre, Tianjin, China.
ANZ J Surg. 2022 Jan;92(1-2):140-145. doi: 10.1111/ans.17274. Epub 2021 Oct 12.
The surgical management of left-sided malignant large bowel obstruction (MLBO) is associated with high morbidity and mortality. Recently, self-expandable metallic colonic stent (SEMS) and transanal decompression tube (TDT) used as a 'bridge to surgery' (BTS) have been widely used. This study aims to compare the clinical outcomes and oncological safety of SEMS and TDT as BTS to transform MLBO into elective surgery.
Between February 2013 and March 2019, 62 patients with MLBO received SEMS (n = 32) or TDT (n = 30), and elective one-stage surgery later. We evaluated decompression efficiency and oncological safety in selective operation in TDT and SEMS groups, including preoperative preparation time, surgical approach, number of lymphatic dissection and vascular invasion, ulcer formation and histopathological findings of resected specimens.
The preoperative preparation time in the SEMS group was shorter than that of the TDT group (P < 0.05). However, there was no significant difference between the groups in postoperative length of hospital stay (P > 0.05). The number of vascular invasions in the TDT group was less than that in the SEMS group (P < 0.05). Furthermore, the risk of wound abscess and ulcer formation in the TDT group was significantly lower than that in the SEMS group (P < 0.05).
Our findings suggest that SEMS is associated with a relatively poor oncological outcome and the placement of TDT as BTS in MLBO patients may be a better alternation.
左侧恶性大肠梗阻(MLBO)的手术治疗与较高的发病率和死亡率相关。最近,自膨式金属结肠支架(SEMS)和经肛门减压管(TDT)作为“桥接手术”(BTS)已被广泛应用。本研究旨在比较 SEMS 和 TDT 作为 BTS 将 MLBO 转化为择期手术的临床效果和肿瘤安全性。
2013 年 2 月至 2019 年 3 月,62 例 MLBO 患者接受了 SEMS(n=32)或 TDT(n=30)治疗,并随后进行了择期一期手术。我们评估了 TDT 和 SEMS 组选择性手术中的减压效率和肿瘤安全性,包括术前准备时间、手术方式、淋巴结清扫和血管侵犯的数量、溃疡形成以及切除标本的组织病理学发现。
SEMS 组的术前准备时间短于 TDT 组(P<0.05)。然而,两组患者的术后住院时间无显著差异(P>0.05)。TDT 组的血管侵犯数量少于 SEMS 组(P<0.05)。此外,TDT 组的伤口脓肿和溃疡形成风险明显低于 SEMS 组(P<0.05)。
我们的研究结果表明,SEMS 与相对较差的肿瘤学结果相关,而在 MLBO 患者中放置 TDT 作为 BTS 可能是更好的选择。