Division of Cardiology, Department of Internal Medicine, Hallym University College of Medicine, Chuncheon, Korea.
Division of Cardiology, Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
J Korean Med Sci. 2021 Oct 11;36(39):e277. doi: 10.3346/jkms.2021.36.e277.
Mass vaccination with the Pfizer-BioNTech coronavirus disease 2019 (COVID-19) vaccine (BNT162b2) in Korea has resulted in many reported adverse effects. These side effects are the object of much scrutiny in the medical community. We report the case of a 29-year-old male who was diagnosed with myopericarditis after his second dose of Pfizer-BioNTech COVID-19 vaccine. This patient is the second recognized case of Pfizer-BioNTech COVID-19 vaccine induced myopericarditis in Korea and the first to have recovered from it. He originally presented with chest discomfort and exertional chest pain. Lab tests revealed elevated cardiac marker levels and echocardiographic findings displayed minimal pericardial effusion, prompting diagnosis as myopericarditis. We decided on two weeks of outpatient treatment with non-steroidal anti-inflammatory drugs (NSAIDs) due to the patient's mild symptoms and his occupation in the military. When this proved insufficient, we shifted to combination therapy with low dose corticosteroids and NSAIDs. After two weeks of treatment, the patient's symptoms and pericardial effusion had improved, and he was recovered completely 37 days after the onset.
在韩国,大规模接种辉瑞-生物科技公司的 2019 年冠状病毒病(COVID-19)疫苗(BNT162b2)导致了许多报告的不良反应。这些副作用是医学界关注的焦点。我们报告了一例 29 岁男性在接种第二剂辉瑞-生物科技公司的 COVID-19 疫苗后被诊断为心肌炎的病例。该患者是韩国第二例被确认的辉瑞-生物科技公司的 COVID-19 疫苗引起的心肌炎病例,也是首例康复的病例。他最初表现为胸痛和劳力性胸痛。实验室检查显示心肌标志物水平升高,超声心动图显示少量心包积液,提示诊断为心肌炎。由于患者症状轻微,且从事军事工作,我们决定对其进行两周的非甾体抗炎药(NSAIDs)门诊治疗。当这种治疗方法效果不佳时,我们转而采用低剂量皮质类固醇和 NSAIDs 的联合治疗。经过两周的治疗,患者的症状和心包积液得到改善,发病 37 天后完全康复。