Department of Cardiovascular Medicine, Chonnam National University Medical School/Hospital, Gwangju, Korea.
Department of Pathology, Chonnam National University Medical School, Gwangju, Korea.
J Korean Med Sci. 2022 Aug 29;37(34):e265. doi: 10.3346/jkms.2022.37.e265.
Post-vaccination myocarditis after administration of the NVX-CoV2373 coronavirus disease 2019 (COVID-19) vaccine has been reported in a limited population. We report the first biopsy-proven case of myopericarditis after administration of second dose of NVX-CoV2373 COVID-19 vaccine (Novavax®) in Korea. A 30-year-old man was referred to emergency department with complaints of chest pain and mild febrile sense for two days. He received the second dose vaccine 17 days ago. Acute myopericarditis by the vaccination was diagnosed by cardiac endomyocardial biopsy. He was treated with corticosteroid 1 mg/kg/day for 5 days and tapered for one week. He successfully recovered and was discharged on the 12th day of hospitalization. The present case suggests acute myopericarditis as a vaccination complication by Novavax® in Korea.
接种 NVX-CoV2373 冠状病毒病 2019（COVID-19）疫苗后出现接种后心肌炎的情况在有限的人群中已有报道。我们报告了首例在韩国接种第二剂 NVX-CoV2373 COVID-19 疫苗（Novavax®）后经活检证实的心肌炎病例。一名 30 岁男性因胸痛和两天轻度发热来急诊就诊。他在 17 天前接种了第二剂疫苗。心脏心内膜心肌活检诊断为疫苗接种引起的急性心肌炎。他接受了 1 毫克/千克/天的皮质类固醇治疗 5 天，并在一周内逐渐减少剂量。他成功康复并在住院第 12 天出院。本病例提示急性心肌炎是韩国 Novavax®疫苗的接种并发症。
