Department of Speech Pathology and Audiology, Faculty of Humanities, University of the Witwatersrand, Johannesburg.
S Afr J Commun Disord. 2021 Sep 30;68(1):e1-e7. doi: 10.4102/sajcd.v68i1.820.
Limited research exists on the sensitivity and specificity of wideband acoustic immittance (WAI) in adults living with human immunodeficiency virus (HIV). This study forms part of the bigger study titled 'wideband acoustic immittance in adults living with HIV'.
To determine the sensitivity and specificity of the wideband absorbance measure at tympanic peak pressure (TPP), as a screening tool for detecting middle ear pathologies in adults living with HIV.
A prospective nonexperimental study comprising 99 adults living with HIV was performed. All participants underwent a basic audiological test battery which included case history, video otoscopy, tympanometry, wideband absorbance at TPP and pure tone audiometry. Middle ear pathologies were established by two otorhinolaryngologists using asynchronous video otoscopic images analysis. The outcomes of the otorhinolaryngologists served as the gold standard against which the wideband absorbance at TPP and tympanometry were measured. The receiver operating characteristics (ROC) curve was calculated.
ROC revealed the sensitivity of wideband absorbance at TPP to be higher in low to mid frequencies, but significantly lower in frequencies above 971.53 Hz. The sensitivity of tympanometry was lower. However, there was no difference between the specificity of wideband absorbance at TPP and tympanometry, indicating that when there are no pathologies, tympanometry is equally accurate.
The current findings reveal that wideband absorbance at TPP can distinguish middle ear pathologies better than the tympanometry. Incorporating wideband absorbance at TPP in clinical practice may improve early identification and intervention of middle ear pathologies.
目前针对人类免疫缺陷病毒(HIV)感染者的宽频声导抗(WAI)的敏感性和特异性的研究有限。本研究是题为“HIV 感染者的宽频声导抗”的更大研究的一部分。
确定宽频声导抗在鼓室峰压(TPP)处的吸光度测量作为检测 HIV 感染者中耳病理的筛查工具的敏感性和特异性。
进行了一项包含 99 名 HIV 感染者的前瞻性非实验性研究。所有参与者均接受了基本的听力学测试,包括病史、视频耳镜检查、鼓室图、TPP 处的宽频吸光度和纯音测听。中耳病理由两名耳鼻喉科医生使用异步视频耳镜图像分析来确定。耳鼻喉科医生的结果作为金标准,测量 TPP 处的宽频吸光度和鼓室图的结果与之进行比较。计算了受试者工作特征(ROC)曲线。
ROC 显示 TPP 处的宽频吸光度在低频到中频时的敏感性较高,但在 971.53 Hz 以上的频率时显著降低。鼓室图的敏感性较低。然而,TPP 处的宽频吸光度和鼓室图的特异性之间没有差异,这表明在没有病理的情况下,鼓室图同样准确。
目前的研究结果表明,TPP 处的宽频吸光度比鼓室图更能区分中耳病理。将 TPP 处的宽频吸光度纳入临床实践可能会改善中耳病理的早期识别和干预。