穴位刺激治疗癌症相关疲劳：随机对照试验的定量综合。
Acupoint stimulation for cancer-related fatigue: A quantitative synthesis of randomised controlled trials.
机构信息
Charles Darwin University, College of Nursing and Midwifery Brisbane Centre, 410 Ann Street, Brisbane, QLD, Australia.
Charles Darwin University, Office of Research and Innovation, Ellengowan Drive, Darwin, NT, Australia.
出版信息
Complement Ther Clin Pract. 2021 Nov;45:101490. doi: 10.1016/j.ctcp.2021.101490. Epub 2021 Oct 7.
BACKGROUND AND PURPOSE
This study aimed to identify the research evidence on acupoint stimulation (AS) for cancer-related fatigue (CRF) management.
METHODS
Randomised controlled trials that utilised AS for CRF management were retrieved. The Cochrane Back Review Group Risk of Bias Tool was used for quality appraisal. RevMan 5.3 was used for meta-analysis.
RESULTS
Fifteen studies were included. Both the overall (SMD = -0.95, p = 0.008) and sub-group (acupuncture: SMD = -1.25, p = 0.002; short-term AS: SMD = -0.95, p = 0.02; medium-term AS: SMD = -0.96, p = 0.003) analyses indicated that AS was more effective in alleviating CRF than standard treatment/care. A comparison between the true and sham AS interventions favoured the true AS for CRF management, although the difference did not reach statistical significance.
CONCLUSION
This study identified a promising role of AS in improving CRF. However, the study findings should be interpreted prudently due to the limited quality and sample sizes of some of the included studies.
背景与目的
本研究旨在确定穴位刺激（AS）在癌症相关疲劳（CRF）管理中的研究证据。
方法
检索了使用 AS 治疗 CRF 的随机对照试验。采用 Cochrane 背部评价组偏倚风险工具进行质量评估。使用 RevMan 5.3 进行荟萃分析。
结果
纳入了 15 项研究。总体（SMD=-0.95，p=0.008）和亚组（针刺：SMD=-1.25，p=0.002；短期 AS：SMD=-0.95，p=0.02；中期 AS：SMD=-0.96，p=0.003）分析均表明，AS 在缓解 CRF 方面比标准治疗/护理更有效。真实与假 AS 干预的比较结果表明，真实 AS 更有利于 CRF 管理，但差异无统计学意义。
结论
本研究发现 AS 在改善 CRF 方面具有一定的作用，但由于部分纳入研究的质量和样本量有限，研究结果应谨慎解释。
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