草药与抗癌药物的协同作用：系统评价和荟萃分析方案。
Synergistic effects of herbal medicines and anticancer drugs: A protocol for systematic review and meta-analysis.
机构信息
Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
出版信息
Medicine (Baltimore). 2021 Nov 19;100(46):e27918. doi: 10.1097/MD.0000000000027918.
BACKGROUND
An increasing number of studies have been reporting combination therapy using herbal medicines and anticancer drugs, and the synergistic effects of this combination have gained much attention across the medical community. In this study, we will review and summarize all published studies that have investigated the synergistic interaction between herbal medicines and anticancer drugs.
METHODS
We will search the PubMed, Embase, and Cochrane Library databases. Studies investigated the synergistic interaction between herbal medicines and anticancer drugs will be included. The selection and extraction process will be performed by 2 independent reviewers, and we will perform qualitative synthesis.
DISCUSSION
The present study is being performed to investigate the herbal medicines and anticancer drugs that are used concomitantly, and to determine the combinations that are expected to show a synergistic effect. This knowledge will provide new insights into the possible role of herbal medicines in anticancer treatment.
REVIEW REGISTRATION
Trial registration: OSF Registration number: DOI 10.17605/OSF.IO/H5QS9.
背景
越来越多的研究报告称，草药和抗癌药物联合治疗，这种联合的协同作用引起了医学界的广泛关注。在这项研究中，我们将回顾和总结所有已发表的研究，这些研究调查了草药和抗癌药物之间的协同相互作用。
方法
我们将搜索 PubMed、Embase 和 Cochrane Library 数据库。将包括研究草药和抗癌药物协同相互作用的研究。选择和提取过程将由 2 位独立评审员进行，我们将进行定性综合分析。
讨论
目前正在进行这项研究，以调查同时使用的草药和抗癌药物，并确定预期具有协同作用的组合。这方面的知识将为草药在抗癌治疗中的可能作用提供新的见解。
综述注册
试验注册：OSF 注册号：DOI 10.17605/OSF.IO/H5QS9。
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