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特发性肺纤维化远程康复计划——一项单中心随机试验。

Tele-Rehabilitation Program in Idiopathic Pulmonary Fibrosis-A Single-Center Randomized Trial.

机构信息

Center for Rare Lung Diseases, Department of Respiratory Diseases and Allergy, Aarhus University Hospital, 8200 Aarhus, Denmark.

Department of Research and Development, Physio R&D ApS, 2000 Frederiksberg, Denmark.

出版信息

Int J Environ Res Public Health. 2021 Sep 23;18(19):10016. doi: 10.3390/ijerph181910016.

DOI:10.3390/ijerph181910016
PMID:34639313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8508000/
Abstract

We investigated the usefulness and effectiveness of tele-rehabilitation on exercise capacity in patients with idiopathic pulmonary fibrosis (IPF). A randomized study was carried out, including stable patients with IPF for 3 months of tele-rehabilitation: video and chat consultations with a physiotherapist and workout sessions with a virtual physiotherapist agent (VAPA). Moreover, 6-min walk test distance (6MWTD), forced vital capacity (FVC), diffusion capacity for carbon monoxide (DLCO), 7 days pedometry, Saint George Respiratory Questionnaire for interstitial lung disease, The King's Brief Interstitial Lung Disease Questionnaire, and General Anxiety Disorder 7 Questionnaire were tested before and after 3 months of tele-rehabilitation, as well as after 3 and 6 months follow-up. Patient satisfaction and adherence were also measured for tele-rehabilitation with VAPA. Twenty-nine patients aged 70.9 ± 8.6 years, male 72.4%, FVC% 83.5 ± 17.7, DLCO% 50.6 ± 13.0, 6MWTD 468.4 ± 14.8 were included. Fifteen patients were randomized to tele-rehabilitation with VAPA and 14 to the control group. Differences in 6MWTD between groups were at baseline (+10 m ( = 0.11)) and after 3 (+39.5 m ( = 0.03)), 6 (+34.3 m ( = 0.02)), and 9 months (+40.5 m ( = 0.15)) follow-up. No difference was observed in pedometry and quality of life. Adherence was above 63%. Patient satisfaction was high. Tele-rehabilitation with VAPA appears to be useful in patients with IPF. Exercise capacity was better at follow up at 3 and 6 months compared with the control group. There was no change in quality of life or pedometry. Adherence and patient satisfaction were all high.

摘要

我们研究了远程康复对特发性肺纤维化(IPF)患者运动能力的有效性和实用性。进行了一项随机研究,包括 3 个月的远程康复:与物理治疗师进行视频和聊天咨询以及与虚拟物理治疗师代理(VAPA)进行锻炼。此外,在 3 个月的远程康复前后以及 3 个月和 6 个月随访时测试了 6 分钟步行测试距离(6MWTD)、用力肺活量(FVC)、一氧化碳弥散量(DLCO)、7 天计步、圣乔治呼吸问卷(用于间质性肺疾病)、金氏简短间质性肺疾病问卷(用于间质性肺疾病)和一般焦虑障碍 7 项问卷。还测量了患者对 VAPA 远程康复的满意度和依从性。29 名年龄 70.9 ± 8.6 岁的患者,男性占 72.4%,FVC%为 83.5 ± 17.7,DLCO%为 50.6 ± 13.0,6MWTD 为 468.4 ± 14.8。15 名患者被随机分配到 VAPA 远程康复组,14 名患者被分配到对照组。组间 6MWTD 的差异在基线时(+10m(=0.11))和 3 个月后(+39.5m(=0.03))、6 个月后(+34.3m(=0.02))和 9 个月后(+40.5m(=0.15))随访时。计步和生活质量没有差异。依从性高于 63%。患者满意度高。VAPA 远程康复似乎对 IPF 患者有用。与对照组相比,在 3 个月和 6 个月随访时,运动能力更好。生活质量或计步没有变化。依从性和患者满意度均较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/a4adfbe3dc3a/ijerph-18-10016-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/9952fc90e70c/ijerph-18-10016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/d7fc0420dca2/ijerph-18-10016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/14717447a23f/ijerph-18-10016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/a4adfbe3dc3a/ijerph-18-10016-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/9952fc90e70c/ijerph-18-10016-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/d7fc0420dca2/ijerph-18-10016-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/14717447a23f/ijerph-18-10016-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b67/8508000/a4adfbe3dc3a/ijerph-18-10016-g004.jpg

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