Department of Nursing, Joongbu University, Geumsan 32716, Korea.
Department of Nursing, Semyung University, Jecheon 27136, Korea.
Int J Environ Res Public Health. 2021 Sep 30;18(19):10315. doi: 10.3390/ijerph181910315.
(1) Objective: Lead, a heavy metal that exists commonly in air, soil and crops may cause chronic disease in the cardiovascular system. The purpose of this study is to investigate how blood lead levels affect cardiovascular disease in adults. (2) Study Design and Participants: It is a cross-sectional, descriptive study using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data from a total of 1929 participants, derived from the KNHANES, conducted by the Korea Centers for Disease Control and Prevention, in 2017, were analyzed using SPSS version 25.0. (3) Measurement: The cardiovascular disease risk was calculated using the Framingham risk score. There was a strong positive correlation between blood lead levels and the Framingham risk score. Furthermore, of the FRS sub-criteria, systolic blood pressure, HDL cholesterol level and total cholesterol level all also showed a significant correlation. (4) Results: We analyzed the correlation between PbB levels and the FRS sub-criteria, including systolic blood pressure, HDL cholesterol level, total cholesterol level and the FRS total. We found a significant positive correlation between PbB levels and systolic blood pressure, FRS total and total cholesterol level ( < 0.05), as well as a significant negative correlation with HDL cholesterol level ( < 0.05). (5) Conclusion: Based on the perception that there is no lower toxicological threshold for blood lead, it is necessary to restrict lead in product manufacturing for the purpose of public health. In addition, it is necessary to be aware of the dangers of exposure to even small amounts of lead in daily life.
(1) 目的：铅是一种常见于空气、土壤和作物中的重金属，可能导致心血管系统的慢性疾病。本研究旨在探讨血铅水平如何影响成年人的心血管疾病。(2) 研究设计和参与者：这是一项使用韩国国家健康和营养检查调查（KNHANES）数据的横断面描述性研究。韩国疾病控制和预防中心于 2017 年进行的 KNHANES 共纳入了 1929 名参与者，我们使用 SPSS 版本 25.0 对这些数据进行了分析。(3) 测量：心血管疾病风险使用弗雷明汉风险评分进行计算。血铅水平与弗雷明汉风险评分呈强正相关。此外，在 FRS 子标准中，收缩压、高密度脂蛋白胆固醇水平和总胆固醇水平也显示出显著相关性。(4) 结果：我们分析了 PbB 水平与 FRS 子标准（包括收缩压、高密度脂蛋白胆固醇水平、总胆固醇水平和 FRS 总分）之间的相关性。我们发现 PbB 水平与收缩压、FRS 总分和总胆固醇水平呈显著正相关（<0.05），与高密度脂蛋白胆固醇水平呈显著负相关（<0.05）。(5) 结论：基于血铅没有更低毒性阈值的认知，为了公共健康，有必要限制产品制造中的铅含量。此外，有必要意识到日常生活中接触少量铅的危害。
