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Gestational Bell's Palsy Is Associated with Higher Blood Pressure during Late Pregnancy and Lower Birth Weight: A Retrospective Case-Control Study.妊娠性贝尔氏面瘫与妊娠晚期血压升高和出生体重降低有关:一项回顾性病例对照研究。
Int J Environ Res Public Health. 2021 Sep 30;18(19):10342. doi: 10.3390/ijerph181910342.
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本文引用的文献

1
Pregnancy Does Not Increase the Risk of Bell's Palsy: A National Cohort Study.妊娠不会增加贝尔麻痹的风险:一项全国队列研究。
Otol Neurotol. 2020 Jan;41(1):e111-e117. doi: 10.1097/MAO.0000000000002421.
2
Innate immune cells in the placental bed in healthy pregnancy and preeclampsia.健康妊娠和子痫前期胎盘床中的固有免疫细胞。
Placenta. 2018 Sep;69:125-133. doi: 10.1016/j.placenta.2018.04.012. Epub 2018 Apr 25.
3
Immune regulation of systemic hypertension, pulmonary arterial hypertension, and preeclampsia: shared disease mechanisms and translational opportunities.系统性高血压、肺动脉高压和子痫前期的免疫调节:共同的疾病机制及转化机会
Am J Physiol Regul Integr Comp Physiol. 2017 Dec 1;313(6):R693-R705. doi: 10.1152/ajpregu.00259.2017. Epub 2017 Oct 4.
4
Bell's palsy in pregnancy: underlying HELLP syndrome or pre-eclampsia?妊娠期贝尔麻痹:潜在的HELLP综合征还是先兆子痫?
Obstet Med. 2013 Sep;6(3):132-133. doi: 10.1258/om.2012.110093. Epub 2013 May 3.
5
Identifying immune mechanisms mediating the hypertension during preeclampsia.确定子痫前期期间介导高血压的免疫机制。
Am J Physiol Regul Integr Comp Physiol. 2016 Jul 1;311(1):R1-9. doi: 10.1152/ajpregu.00052.2016. Epub 2016 Apr 20.
6
Bell's palsy: aetiology, clinical features and multidisciplinary care.贝尔氏麻痹:病因、临床特征和多学科治疗。
J Neurol Neurosurg Psychiatry. 2015 Dec;86(12):1356-61. doi: 10.1136/jnnp-2014-309563. Epub 2015 Apr 9.
7
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy.妊娠期高血压。美国妇产科医师学会妊娠期高血压特别工作组报告
Obstet Gynecol. 2013 Nov;122(5):1122-1131. doi: 10.1097/01.AOG.0000437382.03963.88.
8
Bell's palsy during pregnancy: is it associated with adverse perinatal outcome?妊娠期间发生贝尔氏麻痹:是否与不良围产期结局相关?
Laryngoscope. 2011 Jul;121(7):1395-8. doi: 10.1002/lary.21860. Epub 2011 May 16.
9
Bell's palsy and pregnancy.贝尔氏面瘫与妊娠
Otolaryngol Head Neck Surg. 2007 Dec;137(6):858-61. doi: 10.1016/j.otohns.2007.09.009.
10
Idiopathic facial paralysis (Bell's palsy) in the immediate puerperium in a patient with mild preeclampsia: a case report.一例轻度子痫前期患者产褥早期的特发性面神经麻痹(贝尔麻痹):病例报告
Arch Gynecol Obstet. 2005 Sep;272(3):241-3. doi: 10.1007/s00404-005-0742-2. Epub 2005 May 3.

妊娠性贝尔氏面瘫与妊娠晚期血压升高和出生体重降低有关:一项回顾性病例对照研究。

Gestational Bell's Palsy Is Associated with Higher Blood Pressure during Late Pregnancy and Lower Birth Weight: A Retrospective Case-Control Study.

机构信息

Division of Neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

Department of Obstetrics and Gynecology, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand.

出版信息

Int J Environ Res Public Health. 2021 Sep 30;18(19):10342. doi: 10.3390/ijerph181910342.

DOI:10.3390/ijerph181910342
PMID:34639638
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8507752/
Abstract

The associations between gestational Bell's palsy (GBP) and late obstetric complications (LOCs), i.e., preeclampsia (PE), eclampsia (EC), gestational hypertension (GHT), and gestational diabetes mellitus (GDM) remain unclear. This study aimed to evaluate these associations and the neonatal health of the newborns born from pregnant women with and without GBP. A retrospective 1:5 case-control study matching exact maternal age and gravidity between pregnant women with and without GBP in Songklanagarind Hospital from 2006 to 2016 was conducted. The associations between GBP and PE, EC, GHT, and GDM, as well as comparison of the newborns' health indices were analyzed by bivariate analysis ( < 0.05). Eight GBP cases out of 8,756 pregnant women were recruited. Six GBP cases were first or second gravid. GBP occurred during the third trimester in five cases. Except for higher median systolic blood pressure (125 (114.2, 127.5) vs. (110 (107.0, 116.0), = 0.045) and diastolic blood pressures (77 (73.0, 80.8) vs. 70 (65.0, 73.2), = 0.021) in the GBP cases, associations between GBP and all LOCs could not be concluded due to the lack of power. However, a significantly lower mean birth weight in the newborns of GBP mothers was found (2672.2 (744.0) vs. 3154.8 (464.7), = 0.016) with statistically significant power. Except for the higher blood pressures and lower birth weights of the newborns of GBP mothers, an association between GBP and LOCs remains inconclusive.

摘要

妊娠贝尔氏麻痹(GBP)与晚期产科并发症(LOCs),即子痫前期(PE)、子痫(EC)、妊娠高血压(GHT)和妊娠糖尿病(GDM)之间的关联尚不清楚。本研究旨在评估这些关联以及患有和不患有 GBP 的孕妇所生新生儿的新生儿健康状况。对 2006 年至 2016 年在 Songklanagarind 医院就诊的患有和不患有 GBP 的孕妇进行了回顾性 1:5 病例对照研究,匹配了 exact 母亲年龄和孕次。通过二元分析(<0.05)分析了 GBP 与 PE、EC、GHT 和 GDM 之间的关联,以及新生儿健康指数的比较。从 8756 名孕妇中招募了 8 名 GBP 病例。6 例 GBP 病例为初产妇或经产妇。5 例 GBP 发生在孕晚期。除了 GBP 病例的收缩压中位数较高(125(114.2,127.5)比(110(107.0,116.0),=0.045)和舒张压中位数较高(77(73.0,80.8)比 70(65.0,73.2),=0.021)外,由于缺乏统计学效能,无法得出 GBP 与所有 LOCs 之间存在关联的结论。然而,GBP 母亲的新生儿的平均出生体重明显较低(2672.2(744.0)比 3154.8(464.7),=0.016),且具有统计学意义。除了 GBP 母亲的新生儿血压较高和出生体重较低外,GBP 与 LOCs 之间的关联仍不确定。