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妊娠期间的贝尔麻痹:危险因素、治疗及结局的范围综述

Bell's palsy in pregnancy: A scoping review of risk factors, treatment and outcomes.

作者信息

Jones Holly, Hintze Justin, Slattery Fionn, Gendre Adrien

机构信息

Department of Otolaryngology, Head and Neck Surgery Beaumont Hospital Dublin Ireland.

Royal College of Surgeons in Ireland Dublin Ireland.

出版信息

Laryngoscope Investig Otolaryngol. 2023 Aug 14;8(5):1376-1383. doi: 10.1002/lio2.1136. eCollection 2023 Oct.

Abstract

OBJECTIVE

There are limited studies reporting on Bell's palsy and pregnancy. Our study aimed to evaluate risk factors, current treatment options and facial function outcomes in women who developed Bell's palsy in pregnancy. To our knowledge this is the first review analyzing these factors.

DATA SOURCES/REVIEW METHODS: A search of PubMed/MEDLINE, Embase, Web of Sciences and Scopus was carried out. Studies describing risk factors, treatment and/or facial function outcomes of Bell's palsy in pregnancy were included. PRISMA-Scr guidelines were followed.

RESULTS

The search yielded 392 abstracts, of which 15 studies were included for analysis. It was not possible to perform a meta-analysis due to small numbers and quality of studies. There were 559 patients included from the 15 studies. The third trimester was the most common time for Bell's palsy to occur ( = 364, 65%). Pre-eclampsia was the most common co-morbidity reported. The most common treatment was corticosteroids and the majority of patients had a complete recovery of their palsy (58%,  = 192).

CONCLUSION

This analysis has evaluated all available data concerning risk factors, treatment and facial function outcomes of BP in pregnancy. The third trimester is the most common time for Bell's palsy to occur in pregnancy. There is currently a lack of high quality evidence into this condition in pregnancy.

LEVEL OF EVIDENCE

摘要

目的

关于贝尔面瘫与妊娠的研究报道有限。我们的研究旨在评估妊娠期发生贝尔面瘫的女性的危险因素、当前治疗方案及面部功能结局。据我们所知,这是首次分析这些因素的综述。

数据来源/综述方法:检索了PubMed/MEDLINE、Embase、科学网和Scopus。纳入描述妊娠期贝尔面瘫的危险因素、治疗和/或面部功能结局的研究。遵循PRISMA-Scr指南。

结果

检索得到392篇摘要,其中15项研究纳入分析。由于研究数量少及质量问题,无法进行荟萃分析。15项研究共纳入559例患者。孕晚期是贝尔面瘫最常见的发病时间(n = 364,65%)。子痫前期是最常见的合并症。最常见的治疗方法是使用皮质类固醇,大多数患者面瘫完全恢复(58%,n = 192)。

结论

本分析评估了所有关于妊娠期贝尔面瘫的危险因素、治疗及面部功能结局的现有数据。孕晚期是妊娠期贝尔面瘫最常见的发病时间。目前缺乏关于妊娠期该疾病的高质量证据。

证据级别

1级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb73/10601580/9c77f268c6e3/LIO2-8-1376-g001.jpg

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