Wróblewska-Seniuk Katarzyna, Basiukajć Agnieszka, Wojciechowska Dobrochna, Telge Mayanthi, Miechowicz Izabela, Mazela Jan
Department of Newborns' Infectious Diseases, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
Student Research Club at the Department of Newborns' Infectious Diseases, Poznan University of Medical Sciences, 60-535 Poznan, Poland.
J Clin Med. 2021 Sep 25;10(19):4383. doi: 10.3390/jcm10194383.
(1) Background: According to the literature, most outcomes of neonates born to mothers infected with SARS-CoV-2 are favorable. This study aimed to assess the clinical characteristics of newborns born to infected women in a tertiary center in Poznan, Poland. (2) Methods: The study comprised 101 newborns delivered by women infected with SARS-CoV-2. The control group consisted of 101 newborns born before the pandemic. Data were collected retrospectively from the medical records. (3) Results: Most newborns of SARS-CoV-2-positive mothers were delivered by cesarean section-83.17% vs. 40.59% in the control group ( < 0.05). The groups did not differ in Apgar scores and the need for resuscitation. Newborns of SARS-CoV-2-positive mothers were more likely to present with respiratory distress and require respiratory support. The most common diagnosis was transient tachypnea of the newborn, not correlated with the mode of delivery. Newborns of the study group were never exclusively breastfed, 0% vs. 64.36% ( < 0.05). None of the patients in the study group was tested positive for the virus. (4) Conclusions: Infants born to SARS-CoV-2-positive mothers seem to be more at risk of moderate respiratory failure than other newborns. Separation of mother-baby dyads results in a dramatic fall in breastfeeding in the short-term post-partum period.
(1) 背景：根据文献，感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的母亲所生新生儿的大多数结局良好。本研究旨在评估波兰波兹南一家三级中心中感染女性所生新生儿的临床特征。(2) 方法：该研究纳入了101名由感染SARS-CoV-2的女性分娩的新生儿。对照组由大流行前出生的101名新生儿组成。数据从病历中回顾性收集。(3) 结果：SARS-CoV-2阳性母亲的大多数新生儿通过剖宫产分娩，剖宫产率为83.17%，而对照组为40.59%（P<0.05）。两组在阿氏评分和复苏需求方面无差异。SARS-CoV-2阳性母亲的新生儿更易出现呼吸窘迫并需要呼吸支持。最常见的诊断是新生儿短暂性呼吸急促，与分娩方式无关。研究组的新生儿从未进行纯母乳喂养，比例为0%，而对照组为64.36%（P<0.05）。研究组中没有患者病毒检测呈阳性。(4) 结论：SARS-CoV-2阳性母亲所生婴儿似乎比其他新生儿更易发生中度呼吸衰竭。母婴分离导致产后短期内母乳喂养急剧减少。
