Kadkhodamanesh Azin, Varahrami Vida, Zarei Leila, Peiravian Farzad, Hadidi Mohammad, Yousefi Nazila
School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Economics, Shahid Beheshti University, Tehran, Iran.
J Pharm Policy Pract. 2021 Oct 12;14(1):82. doi: 10.1186/s40545-021-00371-2.
This study estimated the GDP share of pharmaceuticals in Iran based on the drivers of pharmaceutical expenditure and compared it with that of 31 members of the Organisation for Economic Cooperation and Development (OECD).
The factors contributing to pharmaceutical expenditure were identified through literature review and studied by 8 experts to classify the factors. Then, using the panel data method, a model was built to estimate the GDP share of pharmaceutical expenditure based on the extracted factors of the selected countries in Iran's model. To explain the observed differences, several regression analyses were performed based on cross-sectional data. The analyses were performed using EVIEWS software, version 10.
The explanatory variables for the selected countries in the panel model (R = 0.98) were specified. Government health expenditure (β = 0.1432), the share of generic drugs (β = - 0.0143), gross domestic product (GDP) per capita (β = - 0.0058) and the rate of disability-adjusted life-years (DALY) (β = 0.0028) contributed most to pharmaceutical expenditure. In comparison, in the Iranian estimation model (R = 0.84), government health expenditure (β = 0.0536) and the share of generic drugs (β = 0.0369) had a significant impact on pharmaceutical expenditure. In the estimation model with more estimators for Iran (R = 0.99), government health expenditure (β = 0.1694), disease prevalence (β = 0.0537), the share of generic drugs (β = 0.0102), the DALY rate (β = 0.0039), GDP per capita (β = - 0.0033), and the drug price index (β = 0.0007) contribute most to pharmaceutical expenditure.
In the models of the study, factors related to the structure of the healthcare system and the pharmaceutical system contributed most to pharmaceutical expenditure as a share of GDP. Moreover, disease profiles show its predictive role in the second model for Iran.
本研究基于药品支出驱动因素估算了伊朗药品在国内生产总值(GDP)中的占比,并将其与经济合作与发展组织(经合组织)31个成员国的情况进行比较。
通过文献综述确定影响药品支出的因素,并由8位专家进行研究以对这些因素进行分类。然后,使用面板数据方法,基于伊朗模型中所选国家的提取因素构建模型,以估算药品支出在GDP中的占比。为解释观察到的差异,基于横截面数据进行了多项回归分析。分析使用的是EVIEWS软件10版本。
确定了面板模型中所选国家的解释变量(R = 0.98)。政府卫生支出(β = 0.1432)、仿制药占比(β = -0.0143)、人均国内生产总值(GDP)(β = -0.0058)和伤残调整生命年(DALY)率(β = 0.0028)对药品支出的贡献最大。相比之下,在伊朗估算模型(R = 0.84)中,政府卫生支出(β = 0.0536)和仿制药占比(β = 0.0369)对药品支出有显著影响。在针对伊朗的具有更多估算量的估算模型(R = 0.99)中,政府卫生支出(β = 0.1694)、疾病患病率(β = 0.0537)、仿制药占比(β = 0.0102)、DALY率(β = 0.0039)、人均GDP(β = -0.0033)和药品价格指数(β = 0.0007)对药品支出的贡献最大。
在本研究模型中,与医疗保健系统和药品系统结构相关的因素对药品支出占GDP的比例贡献最大。此外,疾病概况在伊朗的第二个模型中显示出其预测作用。