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知识产权保护加强如何影响国家医药支出?OECD 国家分析。

How Does Stronger Protection of Intellectual Property Rights Affect National Pharmaceutical Expenditure? An Analysis of OECD Countries.

机构信息

1 Health Policy Research Department, Korea Institute for Health and Social Affairs, Sejong, Republic of Korea.

2 Department of Health Policy and Management, School of Public Health, Seoul National University, Seoul, Republic of Korea.

出版信息

Int J Health Serv. 2018 Oct;48(4):685-701. doi: 10.1177/0020731418786095. Epub 2018 Jul 6.

Abstract

Intellectual property rights (IPR) protection for pharmaceuticals has been comprehensive and strict since the establishment of the World Trade Organization in 1995 and the subsequent implementation of the TRIPS Agreement. This study investigated the relationship between the level of IPR and national pharmaceutical expenditure using panel data of 22 OECD countries from 1970 to 2009. The patent index was used to measure the level of national protection for IPR along with other covariates: GDP per capita, the percentage of population aged over 65, number of doctors, proportion of public financing among total pharmaceutical expenditure, under-5 mortality, price index, and period indicators. The regression analysis results showed that the level of IPR protection was significantly correlated with pharmaceutical spending even after controlling for various factors that affect pharmaceutical expenditure. The results were consistent in OLS regression and GLS regression. However, the effect of IPR was stronger and more significant in countries with a relatively small-sized pharmaceutical market than in those with big market. Many developed countries incur a financial burden due to rapidly growing pharmaceutical expenditure; therefore, the results of this study present the possibility that stronger IPR would produce welfare loss in developed countries.

摘要

自 1995 年世界贸易组织(WTO)成立和随后实施《与贸易有关的知识产权协定》(TRIPS 协定)以来,药品知识产权(IPR)保护一直非常全面和严格。本研究利用 1970 年至 2009 年期间来自 22 个经合组织(OECD)国家的面板数据,调查了 IPR 水平与国家药品支出之间的关系。采用专利指数衡量国家知识产权保护水平,同时还考虑了其他协变量:人均国内生产总值、65 岁以上人口比例、医生人数、公共筹资占药品总支出的比例、5 岁以下儿童死亡率、价格指数和时期指标。回归分析结果表明,即使在控制了影响药品支出的各种因素之后,知识产权保护水平与药品支出仍显著相关。OLS 回归和 GLS 回归的结果都是一致的。然而,在药品市场规模相对较小的国家,知识产权的作用更强、更显著,而在药品市场规模较大的国家,知识产权的作用则较弱。许多发达国家因药品支出的快速增长而面临财政负担;因此,本研究的结果表明,更强的知识产权可能会给发达国家带来福利损失。

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