Matsuda T, Matsumoto T
Arch Dermatol. 1986 Oct;122(10):1171-5.
A 69-year-old man with acute myeloblastic leukemia was admitted to the hospital for induction chemotherapy. A complication caused by a disseminated mycotic infection occurred while the neutropenic patient was maintained on a course of cytotoxic drugs, antibiotics, and corticosteroid therapy. The causal isolate was identified as Fusarium solani on the basis of its colonial and microscopic morphology. This fungus developed in the patient's tissue in the form of hyaline, branched, septate hyphae. This case fits the definition of the disease entity known as hyalohyphomycosis. The term hyalohyphomycosis encompasses infections caused by various nondematiaceous opportunistic fungi with a filamentous tissue form. The purpose of this article is to review and discuss the literature on hyalohyphomycosis caused by Fusarium species. Combined histopathologic and mycologic findings were evaluated to determine the nature of opportunistic mycotic infections.
一名69岁的急性髓细胞白血病男性患者因诱导化疗入院。在这名中性粒细胞减少的患者接受细胞毒性药物、抗生素和皮质类固醇治疗期间，发生了由播散性霉菌感染引起的并发症。根据其菌落和微观形态，致病分离株被鉴定为茄病镰刀菌。这种真菌在患者组织中以透明、分支、有隔膜的菌丝形式生长。该病例符合被称为透明丝孢霉病的疾病实体的定义。透明丝孢霉病这一术语涵盖了由各种非暗色机会性真菌引起的丝状组织形式的感染。本文的目的是回顾和讨论关于镰刀菌属引起的透明丝孢霉病的文献。综合组织病理学和真菌学检查结果以确定机会性霉菌感染的性质。
