Caux F, Aractingi S, Baurmann H, Reygagne P, Dombret H, Romand S, Dubertret L
Service de Dermatologie, Hôpital Saint Louis, Paris, France.
Dermatology. 1993;186(3):232-5. doi: 10.1159/000247354.
A 47-year-old woman with acute myeloblastic leukemia developed disseminated papules and pustules after chemotherapy. A skin biopsy specimen revealed fungal vasculitis and grew Fusarium solani. The patient died despite treatment with amphotericin B. The isolate was resistant to amphotericin B, imidazole and 5-fluocytosine. Fusarium should be recognized as a potential cause of deep fungal infection in immunocompromised patients.
一名47岁的急性髓细胞白血病女性患者在化疗后出现了弥漫性丘疹和脓疱。皮肤活检标本显示真菌性血管炎，并培养出茄病镰刀菌。尽管使用了两性霉素B进行治疗，患者仍死亡。分离出的菌株对两性霉素B、咪唑和5-氟胞嘧啶耐药。镰刀菌应被视为免疫功能低下患者深部真菌感染的潜在病因。
