Attapattu M C, Anandakrishnan C
J Med Vet Mycol. 1986 Apr;24(2):105-11.
Subcutaneous granulomatous lesions by hyaline moulds are rare. This report describes a case of hyalohyphomycosis by Fusarium oxysporum. The patient was a 16-year-old Sri Lankan girl who had had extensive lesions in both arms almost from infancy. The fungus was demonstrated in KOH mounts and in histopathological sections. It was isolated repeatedly from her lesions over a period of 10 months. Combined therapy with ketoconazole and 5-fluorocytosine resulted in marked improvement. An inherent immune defect is postulated to account for the prolonged and extensive infection by a relatively non-aggressive fungus.
由透明霉菌引起的皮下肉芽肿性病变较为罕见。本报告描述了一例由尖孢镰刀菌引起的透明丝孢霉病。患者是一名16岁的斯里兰卡女孩，几乎从婴儿期起双臂就有广泛病变。在氢氧化钾涂片和组织病理学切片中均发现了该真菌。在10个月的时间里，从她的病变部位反复分离出该真菌。酮康唑和5-氟胞嘧啶联合治疗取得了显著疗效。推测存在先天性免疫缺陷，导致相对不具侵袭性的真菌引发了长期广泛的感染。
