Chao Guanqun, Chen Liying
Department of General Practice, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China.
J Nerv Ment Dis. 2022 Mar 1;210(3):194-198. doi: 10.1097/NMD.0000000000001426.
To further clarify the effectiveness of virtual reality (VR) in improving cognitive function of patients with mild cognitive impairment (MCI) through meta-analysis, we searched the PubMed, Web of Science, Scopus, MEDLINE, and Cochrane centers for controlled trials of VR in patients with MCI. All analyses were performed using RevMan (Version 5.3; Cochrane Collaboration, Oxford, United Kingdom). The selected data were extracted as 2 × 2 table. All included studies were weighted and aggregated. According to the inclusion criteria and exclusion criteria, five articles were selected for meta-analysis. There was no bias or heterogeneity in the results. We found that the diamond is on the right side of the vertical line and does not intersect with the vertical line. We determined the following values: odds ratio, 1.34; 95% confidence interval, 0.31-2.37; z = 2.55; p = 0.01. VR can effectively improve the cognitive function of MCI patients and delay cognitive impairment, which can be further developed as a treatment to delay the development of MCI.
为通过荟萃分析进一步阐明虚拟现实（VR）在改善轻度认知障碍（MCI）患者认知功能方面的有效性，我们检索了PubMed、科学网、Scopus、MEDLINE和Cochrane中心，以查找关于VR治疗MCI患者的对照试验。所有分析均使用RevMan（5.3版；Cochrane协作网，英国牛津）进行。将所选数据提取为2×2表格。对所有纳入研究进行加权和汇总。根据纳入标准和排除标准，选择了五篇文章进行荟萃分析。结果不存在偏倚或异质性。我们发现菱形位于垂直线右侧且与垂直线不相交。我们确定了以下值：比值比为1.34；95%置信区间为0.31 - 2.37；z = 2.55；p = 0.01。VR可有效改善MCI患者的认知功能并延缓认知障碍，可进一步开发作为延缓MCI进展的一种治疗方法。
