Xu L, Han F Y, Wu D, Zhu B Q, Gao W Y, Gao Y, Li Y X, Shao Z J
Institute for Communicable Disease Prevention and Control,Chinese Center for Disease Control and Prevention,Beijing 102206, China.
National Immunization Program, Chinese Center for Disease Control and Prevention,Beijing 100050, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Feb 6;55(2):207-211. doi: 10.3760/cma.j.cn112150-20200922-01227.
To analyze the antimicrobial resistance characteristics of 538 isolated from 2005 to 2019 in China. Total of 538 strains collected from 30 provinces in China from 2005 to 2019. Antimicrobial susceptibility test were performed based on the standards of clinical and laboratory standardization association (CLSI) including 11 recommended antibiotics. Gradient diffusion method was used to detect the antibiotic sensitivity of . All 538 strains were sensitive to azithromycin, meropenem, chloramphenicol, rifampicin and ceftriaxone. As to other six antibiotics, the antibiotics sensitivity rates were cefotaxime (97.4%, 524 strains), ampicillin (87.7%, 472 strains), penicillin (84.8%, 456 strains), minocycline (95.2%, 512 strains), ciprofloxacin (24.9%, 134 strains) and trimethoprim/sulfamethoxazole (11.2%, 60 strains) respectively. isolated from 2005-2019 in China were all sensitive to azithromycin, meropenem, chloramphenicol, rifampicin and ceftriaxone. It should highlight resistant to cefotaxime, ampicillin and penicillin. Ciprofloxacin and sulfamethoxazole are not recommended as the priority choice for clinical treatment and prophylactic medication.
分析2005年至2019年在中国分离出的538株菌株的抗菌耐药性特征。2005年至2019年共从中国30个省份收集了538株菌株。根据临床和实验室标准化协会(CLSI)的标准进行了抗菌药物敏感性试验,包括11种推荐抗生素。采用梯度扩散法检测……的抗生素敏感性。所有538株菌株对阿奇霉素、美罗培南、氯霉素、利福平和头孢曲松敏感。至于其他六种抗生素,抗生素敏感率分别为头孢噻肟(97.4%,524株)、氨苄西林(87.7%,472株)、青霉素(84.8%,456株)、米诺环素(95.2%,512株)、环丙沙星(24.9%,134株)和甲氧苄啶/磺胺甲恶唑(11.2%,60株)。2005 - 2019年在中国分离出的……对阿奇霉素、美罗培南、氯霉素、利福平和头孢曲松均敏感。应强调对头孢噻肟、氨苄西林和青霉素耐药。不建议将环丙沙星和磺胺甲恶唑作为临床治疗和预防性用药的首选。