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环丙沙星、头孢噻肟、头孢曲松、氯霉素和利福平对完全敏感及中度耐青霉素的脑膜炎奈瑟菌的体外活性。

In vitro activities of ciprofloxacin, cefotaxime, ceftriaxone, chloramphenicol, and rifampin against fully susceptible and moderately penicillin-resistant Neisseria meningitidis.

作者信息

Blondeau J M, Yaschuk Y

机构信息

Department of Clinical Microbiology, St. Paul's Hospital (Grey Nuns') Saskatoon, Saskatchewan, Canada.

出版信息

Antimicrob Agents Chemother. 1995 Nov;39(11):2577-9. doi: 10.1128/AAC.39.11.2577.

DOI:10.1128/AAC.39.11.2577
PMID:8585750
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC162989/
Abstract

Moderately penicillin-resistant Neisseria meningitidis was responsible for an outbreak of meningococcal disease in Saskatoon, Saskatchewan, Canada in 1993. We tested fully susceptible and moderately resistant strains of N. meningitidis against ciprofloxacin, cefotaxime, ceftriaxone, chloramphenicol, penicillin, and rifampin. Eighteen percent of the isolates were moderately resistant to penicillin (MIC > or = 0.06 microgram/ml) whereas susceptibility was 100% for the other agents tested.

摘要

1993年，中度耐青霉素的脑膜炎奈瑟菌在加拿大萨斯喀彻温省萨斯卡通市引发了一场脑膜炎球菌病疫情。我们对完全敏感和中度耐药的脑膜炎奈瑟菌菌株进行了环丙沙星、头孢噻肟、头孢曲松、氯霉素、青霉素和利福平的测试。18%的分离株对青霉素中度耐药（最低抑菌浓度≥0.06微克/毫升），而对其他测试药物的敏感性为100%。

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本文引用的文献

1
E test as susceptibility test and epidemiologic tool for evaluation of Neisseria meningitidis isolates.E试验作为评估脑膜炎奈瑟菌分离株的药敏试验和流行病学工具。
J Clin Microbiol. 1993 Dec;31(12):3255-9. doi: 10.1128/jcm.31.12.3255-3259.1993.
2
Meningococcal disease in Malawi: studies on the genetic relatedness of the bacteria.
Ann Trop Med Parasitol. 1994 Feb;88(1):59-64. doi: 10.1080/00034983.1994.11812836.
3
Prevalence of Neisseria meningitidis relatively resistant to penicillin in the United States, 1991. Meningococcal Disease Study Group.1991年美国对青霉素相对耐药的脑膜炎奈瑟菌的流行情况。脑膜炎球菌病研究小组。
J Infect Dis. 1994 Feb;169(2):438-41. doi: 10.1093/infdis/169.2.438.
4
Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, Canada.加拿大萨斯喀彻温省对青霉素敏感性降低的脑膜炎奈瑟菌。
J Clin Microbiol. 1995 Jul;33(7):1784-6. doi: 10.1128/jcm.33.7.1784-1786.1995.
5
Isolation of Neisseria meningitidis strains with increase of penicillin minimal inhibitory concentrations.分离出青霉素最低抑菌浓度升高的脑膜炎奈瑟菌菌株。
Epidemiol Infect. 1987 Oct;99(2):463-9. doi: 10.1017/s0950268800067960.
6
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7
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J Infect Dis. 1987 Jul;156(1):211-3. doi: 10.1093/infdis/156.1.211.
8
Penicillin resistance in Neisseria meningitidis.
N Engl J Med. 1991 Apr 4;324(14):997. doi: 10.1056/NEJM199104043241416.
9
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10
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Clin Infect Dis. 1992 Feb;14(2):394-402. doi: 10.1093/clinids/14.2.394.