伴有既往精神疾病的哺乳期女性停用多潘立酮：病例报告。
Domperidone Withdrawal in a Nursing Female with Pre-existing Psychiatric Illness: A Case Report.
机构信息
Department of Psychiatry, Western University, Ontario, ON, Canada.
Department of Obstetrics and Gynecology, Mc- Master University, Ontario, ON, Canada.
出版信息
Curr Drug Saf. 2022;17(3):278-280. doi: 10.2174/1574886316666211013120735.
BACKGROUND
In this report, we describe a case of domperidone withdrawal in a woman with a history of major depressive disorder and obsessive-compulsive disorder (OCD), who experienced a recurrence of these disorders after stopping domperidone.
CASE PRESENTATION
The symptoms improved after the restarting of domperidone and disappeared gradually as the drug was tapered and discontinued. Clinicians should consider domperidone withdrawal a differential diagnosis in women with a history of depression or anxiety who present with an acute onset of these symptoms following the abrupt discontinuation of domperidone.
CONCLUSION
A gradual taper off of the drug may be effective in minimizing withdrawal symptoms and obviate the need for psychotropic drug use.
背景
在本报告中，我们描述了一例多潘立酮停药病例，该患者有重度抑郁障碍和强迫症（OCD）病史，在停用多潘立酮后这些疾病复发。
病例介绍
重新开始使用多潘立酮后，患者的症状改善，随着药物逐渐减量和停用，症状逐渐消失。对于有抑郁或焦虑病史的女性，如果在突然停用多潘立酮后出现这些症状急性发作，临床医生应考虑多潘立酮停药作为鉴别诊断。
结论
逐渐减少药物剂量可能有助于最大限度减少停药症状，避免使用精神药物。
Zotero 插件