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A critical review of the pathophysiology of thrombotic complications and clinical practice recommendations for thromboprophylaxis in pregnant patients with COVID-19.COVID-19 孕妇血栓并发症的病理生理学综述及血栓预防的临床实践推荐
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Thromboinflammation in COVID-19 acute lung injury.新型冠状病毒肺炎急性肺损伤中的血栓炎症反应。
Paediatr Respir Rev. 2020 Sep;35:20-24. doi: 10.1016/j.prrv.2020.06.004. Epub 2020 Jun 11.
3
Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status - United States, January 22-June 7, 2020.美国 2020 年 1 月 22 日-6 月 7 日,按妊娠状况划分的实验室确诊感染 SARS-CoV-2 的育龄期妇女特征。
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Prevention, Diagnosis, and Treatment of VTE in Patients With Coronavirus Disease 2019: CHEST Guideline and Expert Panel Report.新型冠状病毒肺炎患者静脉血栓栓塞症的预防、诊断和治疗:CHEST 指南和专家报告。
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Public Health Agency of Sweden's Brief Report: Pregnant and postpartum women with severe acute respiratory syndrome coronavirus 2 infection in intensive care in Sweden.瑞典公共卫生局简讯:瑞典重症监护病房中严重急性呼吸综合征冠状病毒 2 感染的孕妇和产后妇女。
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妊娠期重症及危重症 COVID-19:来自蒙特利尔的病例系列

Severe and critical COVID-19 in pregnancy: A case series from Montreal.

作者信息

Trahan Marie-Julie, Malhamé Isabelle, Mitric Cristina, Simard Camille, Lipes Jed, Abenhaim Haim A

机构信息

Department of Obstetrics and Gynecology, McGill University, Montreal, Canada.

Department of Medicine, McGill University, Montreal, Canada.

出版信息

Obstet Med. 2021 Sep;14(3):170-176. doi: 10.1177/1753495X21990213. Epub 2021 Mar 9.

DOI:10.1177/1753495X21990213
PMID:34646346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8504303/
Abstract

BACKGROUND

Optimal obstetric management for women with coronavirus disease (COVID-19) is not known. We describe the management of six pregnant women requiring in-hospital care for severe COVID-19.

METHODS

A retrospective chart review was conducted to identify pregnant women who tested positive for Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2) between 15 March and 30 June 2020. A subset of women meeting criteria for severe COVID-19 was included.

RESULTS

Four women required non-invasive supplemental oxygen therapy and two required mechanical ventilation. Four women were discharged from hospital undelivered and two required preterm delivery. One woman had a pulmonary embolism, and two required re-admission for worsening symptoms.

CONCLUSION

Management of pregnant women with severe COVID-19 is complex and should involve multidisciplinary expertise. Avoiding early delivery may be a safe option. We recommend an individualized approach to care, including careful consideration of the expected risks and benefits of expectant obstetric management versus delivery.

摘要

背景

冠状病毒病(COVID-19)孕妇的最佳产科管理方法尚不清楚。我们描述了六名因重症COVID-19需要住院治疗的孕妇的管理情况。

方法

进行了一项回顾性病历审查,以确定2020年3月15日至6月30日期间严重急性呼吸综合征冠状病毒(SARS-CoV-2)检测呈阳性的孕妇。纳入了符合重症COVID-19标准的一部分女性。

结果

四名女性需要无创补充氧气治疗,两名需要机械通气。四名女性未分娩即出院,两名需要早产。一名女性发生肺栓塞,两名因症状恶化需要再次入院。

结论

重症COVID-19孕妇的管理很复杂,应涉及多学科专业知识。避免过早分娩可能是一个安全的选择。我们建议采用个体化的护理方法,包括仔细考虑期待性产科管理与分娩的预期风险和益处。