Wong Gordon S, Yudina Svetlana V, Reyes Maria Cecilia D
School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY.
Department of General Surgery, University of Rochester Medicine/Noyes Health, Dansville, NY.
ACG Case Rep J. 2021 Oct 5;8(9):e00670. doi: 10.14309/crj.0000000000000670. eCollection 2021 Sep.
Primary leiomyosarcomas of the colon (PLC) are rare tumors, representing 0.12% of all colon malignancies. We report a 59-year-old man with weight loss, mild anemia, and rectal bleeding. Colonoscopy revealed a 3.2 × 2.6-cm mass at the ileocecal valve. Histopathological examination of the biopsy showed a spindle cell neoplasm that stained positive for smooth muscle actin, caldesmon, and desmin. A diagnosis of PLC was made. Subsequently, a laparoscopic right hemicolectomy was performed, and no local recurrence was noted 6 months after the resection. Given the rarity of PLC, more studies on the clinical features and treatments of this tumor are warranted.
原发性结肠平滑肌肉瘤(PLC)是罕见肿瘤,占所有结肠恶性肿瘤的0.12%。我们报告一名59岁男性,有体重减轻、轻度贫血和直肠出血症状。结肠镜检查发现回盲瓣处有一个3.2×2.6厘米的肿块。活检的组织病理学检查显示为梭形细胞瘤,平滑肌肌动蛋白、钙调蛋白和结蛋白染色呈阳性。确诊为PLC。随后进行了腹腔镜右半结肠切除术,切除术后6个月未发现局部复发。鉴于PLC的罕见性,有必要对该肿瘤的临床特征和治疗进行更多研究。