Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Takaramachi 13-1, Kanazawa 920-8640, Japan.
Department of Cardiology, Osaka Saiseikai Senri Hospital, Tukumodai.1-1-6, Suita 565-0862, Japan.
Resuscitation. 2022 Mar;172:106-114. doi: 10.1016/j.resuscitation.2021.10.003. Epub 2021 Oct 11.
As asphyxial cardiac arrest is more common than cardiac arrest from a primary cardiac event in paediatric cardiac arrest, effective ventilation is important during paediatric cardiopulmonary resuscitation (CPR). We aimed to determine optimal dispatcher-assisted CPR instructions for bystanders after paediatric out-of-hospital cardiac arrest (OHCA).
We analysed the records of 8172 children who received bystander dispatcher-assisted CPR. Data were obtained from an All-Japan Utstein-style registry from 2005 to 2017. Patients were divided into conventional CPR and compression-only CPR groups. The primary study endpoint was 1-month neurologically intact survival, defined as a Cerebral Performance Category score of 1 or 2 (CPC 1-2).
The 1-month CPC 1-2 rate was significantly higher in the dispatcher-assisted conventional CPR group than in the dispatcher-assisted compression-only CPR group (before propensity score matching, 5.7% [175/3077] vs. 3.1% [160/5095], p < 0.0001, adjusted odds ratio 2.48, 95% confidence interval 1.19-3.22; after propensity score matching, 6.0% [156/2618] vs. 2.6% [69/2618], p < 0.0001, adjusted odds ratio 2.42, 95% confidence interval 1.76-3.32). In most subgroup analyses after matching, dispatcher-assisted conventional CPR had a higher CPC 1-2 rate than dispatcher-assisted compression-only CPR; however, CPC 1-2 rates were similar between the two groups for patients with an initial shockable rhythm, those with total prehospital CPR time ≥ 20 min, those receiving public access defibrillation, advanced airway management, or adrenaline administration.
Within the limitations of this retrospective observational study, dispatcher-assisted conventional CPR was preferable to dispatcher-assisted compression-only CPR as optimal CPR instructions for coaching callers to perform bystander CPR.
由于窒息性心搏骤停在儿科心搏骤停中比原发性心搏骤停更为常见,因此在儿科心肺复苏(CPR)期间有效的通气非常重要。我们旨在确定儿科院外心搏骤停(OHCA)后,调度员辅助的旁观者 CPR 指令的最佳方案。
我们分析了 8172 名接受过旁观者调度员辅助 CPR 的儿童的记录。这些数据来自于 2005 年至 2017 年期间的全日本乌斯泰因式注册。患者分为常规 CPR 和单纯按压 CPR 组。主要研究终点为 1 个月时神经功能完整存活,定义为脑功能分类评分 1 或 2 级(CPC 1-2)。
在调度员辅助常规 CPR 组中,1 个月时 CPC 1-2 率明显高于调度员辅助单纯按压 CPR 组(在进行倾向评分匹配之前,5.7%[175/3077] vs. 3.1%[160/5095],p<0.0001,调整后优势比 2.48,95%置信区间 1.19-3.22;在进行倾向评分匹配之后,6.0%[156/2618] vs. 2.6%[69/2618],p<0.0001,调整后优势比 2.42,95%置信区间 1.76-3.32)。在匹配后的大多数亚组分析中,调度员辅助常规 CPR 组的 CPC 1-2 率高于调度员辅助单纯按压 CPR 组;然而,在初始可除颤节律、总院前 CPR 时间≥20 分钟、接受公共获取除颤、高级气道管理或肾上腺素给药的患者中,两组的 CPC 1-2 率相似。
在本回顾性观察研究的限制范围内,调度员辅助常规 CPR 优于调度员辅助单纯按压 CPR,是指导呼叫者进行旁观者 CPR 的最佳 CPR 指导。