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在肯尼亚一家县级教学和转诊医院就诊的成年糖尿病患者的糖尿病知识、药物依从性和血糖控制影响因素:一项横断面研究。

Factors impacting on diabetes knowledge, medication adherence and glycemic control among adult diabetics visiting a county teaching and referral hospital in Kenya: a cross-sectional study.

机构信息

Coast Teaching and Referral Hospital, P.O. Box 90231-80100, Mombasa, Kenya.

School of Pharmacy, University of Nairobi, P.O. Box 19676-00202, Nairobi, Kenya.

出版信息

Pan Afr Med J. 2021 Sep 2;40:5. doi: 10.11604/pamj.2021.40.5.21848. eCollection 2021.

Abstract

INTRODUCTION

optimal management of diabetes involves interplay between patients' understanding of their disease and medication adherence, which would eventually influence glycemic control. However, there is scant published literature on the interconnection of patient related factors that impact on optimal management of diabetes in resource-limited settings such as Kenya.

METHODS

a hospital based cross-sectional survey involving 270 freely consenting adult diabetics investigated the interconnection between diabetes knowledge, medication adherence and glycemic control. Data on the patient´s knowledge and medication adherence was collected using validated tools whilst glycemic control was evaluated using the patients' glycated haemoglobin values. Data analysis was carried out using STATA version 13 statistical software, employing the chi square test for association and simple linear regression for prediction, with p ≤0.05 considered significant.

RESULTS

participants´ level of knowledge on diabetes was significantly associated with the academic achievement (p=0.001), while their medication adherence was significantly associated with family support (p=0.001) and duration of disease since diagnosis (p=0.019). On linear regression, family support occasioned by the nature of participants' household setup, had a strong positive correlation [r=0.99 (CI 0.60-1.00)] with optimal glycemic control.

CONCLUSION

family support is an important determinant of medication adherence and optimal glycemic control among diabetic patients. Clinicians should team up with family members of diabetic patients for optimal glycemic control.

摘要

引言

糖尿病的最佳管理涉及患者对疾病的理解和药物依从性的相互作用,这最终会影响血糖控制。然而,在肯尼亚等资源有限的环境中,关于影响糖尿病最佳管理的患者相关因素之间的相互关系的文献很少。

方法

一项基于医院的横断面调查涉及 270 名自愿参与的成年糖尿病患者,调查了糖尿病知识、药物依从性和血糖控制之间的相互关系。使用经过验证的工具收集患者的知识和药物依从性数据,而血糖控制则通过患者的糖化血红蛋白值进行评估。使用 STATA 版本 13 统计软件进行数据分析,采用卡方检验进行关联分析,采用简单线性回归进行预测,p≤0.05 被认为具有统计学意义。

结果

参与者的糖尿病知识水平与学业成绩显著相关(p=0.001),而他们的药物依从性与家庭支持(p=0.001)和自诊断以来的疾病持续时间显著相关(p=0.019)。在线性回归中,参与者家庭结构所带来的家庭支持与最佳血糖控制呈强烈正相关[r=0.99(CI 0.60-1.00)]。

结论

家庭支持是糖尿病患者药物依从性和最佳血糖控制的重要决定因素。临床医生应与糖尿病患者的家庭成员合作,以实现最佳血糖控制。

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