Division of Infectious Diseases, I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Hamburg, Germany.
Euro Surveill. 2021 Oct;26(41). doi: 10.2807/1560-7917.ES.2021.26.41.2002041.
Background spp. are aquatic bacteria that prefer warm seawater with moderate salinity. In humans, they can cause gastroenteritis, wound infections, and ear infections. During the summers of 2018 and 2019, unprecedented high sea surface temperatures were recorded in the German Baltic Sea.AimWe aimed to describe the clinical course and microbiological characteristics of infections in Germany in 2018 and 2019.MethodsWe performed an observational retrospective multi-centre cohort study of patients diagnosed with domestically-acquired infections in Germany in 2018 and 2019. Demographic, clinical, and microbiological data were assessed, and isolates were subjected to whole genome sequencing and antimicrobial susceptibility testing.ResultsOf the 63 patients with infections, most contracted the virus between June and September, primarily in the Baltic Sea: 44 (70%) were male and the median age was 65 years (range: 2-93 years). Thirty-eight patients presented with wound infections, 16 with ear infections, six with gastroenteritis, two with pneumonia (after seawater aspiration) and one with primary septicaemia. The majority of infections were attributed to (non-O1/non-O139) (n = 30; 48%) or (n = 22; 38%). Phylogenetic analyses of 12 available isolates showed clusters of three identical strains of , which caused wound infections, suggesting that some clonal lines can spread across the Baltic Sea.ConclusionsDuring the summers of 2018 and 2019, severe heatwaves facilitated increased numbers of infections in Germany. Since climate change is likely to favour the proliferation of these bacteria, a further increase in -associated diseases is expected.
背景 spp. 是喜欢温暖海水和中等盐度的水生细菌。在人类中,它们可引起肠胃炎、伤口感染和耳部感染。在 2018 年和 2019 年的夏季,德国波罗的海创下了前所未有的高海面温度纪录。
目的 我们旨在描述 2018 年和 2019 年德国感染的临床过程和微生物学特征。
方法 我们对 2018 年和 2019 年在德国诊断为本地获得性感染的患者进行了一项观察性回顾性多中心队列研究。评估了人口统计学、临床和微生物学数据,并对分离株进行了全基因组测序和药敏试验。
结果 在 63 例感染患者中,大多数患者在 6 月至 9 月期间感染了病毒,主要在波罗的海地区:44 例(70%)为男性,中位年龄为 65 岁(范围:2-93 岁)。38 例患者出现伤口感染,16 例患者出现耳部感染,6 例患者出现肠胃炎,2 例患者出现肺炎(海水吸入后),1 例患者出现原发性败血症。大多数感染归因于非 O1/非 O139 型(n=30;48%)或 O157 型(n=22;38%)。12 个可用分离株的系统发育分析显示,引起伤口感染的三个相同菌株的聚类,表明一些克隆系可以在波罗的海传播。
结论 在 2018 年和 2019 年的夏季,严重的热浪导致德国感染病例增加。由于气候变化可能有利于这些细菌的增殖,预计与相关的疾病会进一步增加。