School of Public Health, College of Medicine and Health Sciences, Wachemo University, Hosanna, Ethiopia.
School of Public Health, College of Medicine and Health Sciences Hawassa, Hawassa University, Hawassa, Ethiopia.
PLoS One. 2021 Oct 15;16(10):e0258576. doi: 10.1371/journal.pone.0258576. eCollection 2021.
Following the introduction of Highly Active Anti Retro Viral Treatment (HAART), the survival of people living with HIV/AIDS (PLHIV) has improved. However, hypertension remains a major challenge for people living with HIV. Very little effort has been made to examine the magnitude of hypertension and its contributing factors among clients receiving HAART, particularly in southern Ethiopia. Hence, the current study aimed at determining the frequency of Hypertension and associated factors among clients receiving HAART at Wachemo University Nigist Eleni Mohammed Memorial Referral Hospital, southern Ethiopia, 2020.
A hospital-based cross-sectional study took place from January 20- March 20, 2020. A systematic sampling technique was employed in the selection of 397 clients. Interviewer administered pretested structured questionnaire was used for data collection. Blood pressure and anthropometric parameters of PLHIV were measured. The data was encoded and entered using Epi Data Version 3.1 and exported to SPSS version 23 for analysis. Then bivariable and multivariable logistic regression analyses were used to identify associated factors. Adjusted Odds Ratio (AOR) with 95% CI was used to present the estimated effect size and declare the presence of statistically significant association respectively.
The magnitude of hypertension among clients on HAART was 11.0% 95% CI [7.93, 14.04]. Being on HAART for at least 60 months (AOR: 2.57, 95% CI: 1.24-5.21), being on TDF/3TC/EFV combination (AOR: 4.61, 95% CI: 2.52-8.3), and high alcohol consumption (AOR: 4.31, 95% CI: 1.84-10.02) were identified as significant predictors of hypertension among clients on HAART.
The magnitude of hypertension in the study area was in a considerable state to plan and implement intervention measures. For those clients who have received TDF/3TC/EFV and TDF/3TC/NVP and those who have been on HAART for 60 months, a strong emphasis should be placed on planning a strict follow-up. A concerted effort among health care providers is needed through counseling and education to discourage the habit of high alcohol consumption among clients.
随着高效抗逆转录病毒治疗（HAART）的引入，艾滋病毒/艾滋病感染者（PLHIV）的生存状况得到了改善。然而，高血压仍然是 HIV 感染者面临的主要挑战。在接受 HAART 的患者中，很少有人努力检查高血压的严重程度及其相关因素，特别是在埃塞俄比亚南部。因此，本研究旨在确定 2020 年在埃塞俄比亚南部 Wachemo 大学 Nigist Eleni Mohammed 纪念转诊医院接受 HAART 的患者中高血压的频率及其相关因素。
这是一项 2020 年 1 月 20 日至 3 月 20 日进行的基于医院的横断面研究。采用系统抽样技术选择了 397 名患者。使用经过预测试的结构化问卷进行数据收集。测量 PLHIV 的血压和人体测量参数。数据进行编码并输入 Epi Data 版本 3.1，然后导出到 SPSS 版本 23 进行分析。然后进行单变量和多变量逻辑回归分析，以确定相关因素。使用调整后的优势比（AOR）和 95%置信区间（CI）表示估计的效应大小，并分别表示存在统计学显著关联。
接受 HAART 的患者中高血压的发生率为 11.0%（95%CI[7.93,14.04]）。接受 HAART 至少 60 个月（AOR：2.57，95%CI：1.24-5.21）、接受 TDF/3TC/EFV 联合治疗（AOR：4.61，95%CI：2.52-8.3）和高酒精摄入（AOR：4.31，95%CI：1.84-10.02）被确定为接受 HAART 的患者中高血压的显著预测因素。
研究地区高血压的发生率相当高，需要计划和实施干预措施。对于那些接受 TDF/3TC/EFV 和 TDF/3TC/NVP 治疗且接受 HAART 治疗 60 个月的患者，应高度重视计划严格的随访。需要医疗保健提供者共同努力，通过咨询和教育劝阻患者饮酒过量的习惯。
