Department of Midwifery, College of Medicine and Health Sciences, Wachemo University, Hosanna, Ethiopia.
Department of Pharmacy, College of Medicine and Health Sciences, Wachemo University, Hosanna, Ethiopia.
BMC Pregnancy Childbirth. 2021 Jan 7;21(1):35. doi: 10.1186/s12884-020-03503-9.
Preterm birth is defined as the birth of a baby before 37 completed weeks of gestation. Worldwide, prematurity is the second foremost cause of death in children under the age of 5 years. Preterm birth also gives rise to short and long term complications. Therefore, the primary aim of this study was to identify the factors associated with preterm birth in Wachemo University Nigist Eleni Mohammed Memorial referral hospital, Hadiya Zone, Southern Ethiopia.
An institution-based unmatched case-control study was conducted from July 01, 2018 to June 30, 2019 among mothers who gave birth in Wachemo University Nigest Eleni Mohammed Memorial referral hospital. A retrospective one-year data was retrieved from medical records of mothers with their index neonates. Simple random sampling technique was employed to recruit study participants. SPSS version 20 software was used for data entry and computing statistical analysis. Both bivariable and multivariable logistic regression analyses were used to determine the association of each independent variable with the dependent variable. Odds ratio with their 95% confidence intervals was computed to identify the presence and strength of association, and statistical significance was affirmed if p < 0.05.
The current study evaluated 213 medical records of mothers with index neonates (71 cases and 142 controls). Urban residency [AOR = 0.48; 95% Cl; 0.239, 0.962], antenatal care follow up [AOR = 0.08; 95 Cl; 0.008, 0.694], premature rupture of membranes [AOR = 3.78; 95% Cl; 1.467, 9.749], pregnancy induced hypertension [AOR = 3.77; 95% Cl; 1.408, 10.147] and multiple pregnancies [AOR = 5.53; 95% Cl; 2.467, 12.412] were the factors associated with preterm birth. More than one-third (36.6%) preterm neonates died in the present study.
The present study found that urban residency, antenatal care follow up, premature rupture of membranes, pregnancy induced hypertension and multiple pregnancies were factors associated with preterm birth. The mortality among preterm neonates is high. Enhancing antenatal care follow up and early detection and treatment of disorders among pregnant women during antenatal care and undertaking every effort to improve outcomes of preterm birth and reduce neonatal mortality associated with prematurity is decisive.
早产是指在妊娠 37 周完成之前出生的婴儿。在全球范围内，早产儿是 5 岁以下儿童死亡的第二大主要原因。早产还会导致短期和长期并发症。因此，本研究的主要目的是确定在埃塞俄比亚南部哈迪亚地区 Wachemo 大学 Nigist Eleni Mohammed 纪念转诊医院与早产相关的因素。
这是一项 2018 年 7 月 1 日至 2019 年 6 月 30 日在 Wachemo 大学 Nigest Eleni Mohammed 纪念转诊医院分娩的母亲中进行的基于机构的病例对照研究。从母亲及其索引新生儿的病历中检索了为期一年的回顾性数据。采用简单随机抽样技术招募研究参与者。使用 SPSS 版本 20 软件输入和计算统计分析数据。采用单变量和多变量逻辑回归分析来确定每个自变量与因变量的关联。计算比值比及其 95%置信区间以确定存在和关联强度，如果 p<0.05，则确认统计学意义。
本研究评估了 213 份有索引新生儿的母亲病历（71 例病例和 142 例对照）。城市居住[比值比（AOR）=0.48；95%置信区间；0.239,0.962]、产前保健随访[AOR=0.08；95%置信区间；0.008,0.694]、胎膜早破[AOR=3.78；95%置信区间；1.467,9.749]、妊娠高血压[AOR=3.77；95%置信区间；1.408,10.147]和多胎妊娠[AOR=5.53；95%置信区间；2.467,12.412]是与早产相关的因素。在本研究中，超过三分之一（36.6%）的早产儿死亡。
本研究发现，城市居住、产前保健随访、胎膜早破、妊娠高血压和多胎妊娠是与早产相关的因素。早产儿的死亡率很高。加强产前保健随访，及早发现和治疗产前孕妇的疾病，并尽一切努力改善早产结局，降低与早产相关的新生儿死亡率，这是至关重要的。
