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妊娠与慢性肾脏病:侯凡凡院士的临床与科研成就

Pregnancy and CKD: Advances in Care and the Legacy of Dr Susan Hou.

机构信息

Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan.

Department of Women and Children's Health, King's College London, London, United Kingdom; Department of Renal Medicine, King's College Hospital NHS Foundation Trust, London, United Kingdom.

出版信息

Am J Kidney Dis. 2021 Dec;78(6):865-875. doi: 10.1053/j.ajkd.2021.07.016. Epub 2021 Oct 14.

Abstract

Dr Susan Hou began her illustrious nephrology career at a time when pregnancy in women with chronic kidney disease (CKD) was hazardous and actively discouraged. Her pioneering research in women's health provided much of the early outcome data that shaped our current understanding of CKD and pregnancy. Although many uncertainties regarding optimal management of this vulnerable patient group remain, recent decades have witnessed important advances and renewed interest in improving care for pregnant women with CKD. Many nephrologists have been inspired by Dr Hou's lifetime of work and are grateful for her generous collaborations. In this In Practice Review, we honor her legacy by providing an update of current literature and clinical management guidance in the context of a clinical case vignette that challenges us to consider the many complex aspects to the counseling and care of women with CKD who desire a pregnancy.

摘要

侯淑英博士在女性慢性肾脏病(CKD)患者妊娠风险高且不被鼓励的时代开始了她辉煌的肾病学职业生涯。她在女性健康方面的开创性研究提供了大量早期结果数据,这些数据塑造了我们目前对 CKD 和妊娠的理解。尽管在这个脆弱的患者群体的最佳管理方面仍存在许多不确定因素,但近几十年来,人们对改善 CKD 孕妇的护理重新产生了兴趣并取得了重要进展。许多肾病学家受到侯博士毕生工作的启发,并对她的慷慨合作表示感谢。在本次实践综述中,我们通过一个临床病例描述提供了当前文献和临床管理指南的更新,该病例描述挑战我们考虑希望妊娠的 CKD 女性的咨询和护理的许多复杂方面,以此向她致敬。

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