Critical Care, BluePearl Veterinary Partners, New York, New York, USA.
J Vet Emerg Crit Care (San Antonio). 2022 Jan;32(1):135-140. doi: 10.1111/vec.13143. Epub 2021 Oct 17.
To describe a case of inappropriate antidiuretic hormone (ADH) secretion in a dog secondary to trauma.
A 14-year-old neutered female mixed breed dog presented for evaluation of bite wounds. The dog sustained multiple puncture wounds to the cervical area, stifle, and elbow. Treatment was initiated with isotonic crystalloid fluids, analgesia, broad-spectrum antimicrobials, and gastroprotectants. The dog developed hyponatremia with concurrent serum hypoosmolality and inappropriate urine hyperosmolality and urine sodium secretion, leading to a diagnosis of the syndrome of inappropriate ADH secretion. The hyponatremia improved, and the dog improved clinically and was discharged 3 days after admission.
This is the first case description of the syndrome of inappropriate ADH secretion in a dog suffering from trauma. Inappropriate ADH secretion is largely under-recognized in veterinary patients. Increased awareness of this syndrome can lead to initiation of appropriate treatment and improved outcomes.
描述一例因创伤继发于犬的抗利尿激素（ADH）不适当分泌。
一只 14 岁已绝育的雌性混种犬因咬伤就诊。该犬的颈部、膝关节和肘部有多发性穿刺伤。治疗开始时给予等渗晶体液、镇痛剂、广谱抗生素和胃保护剂。该犬出现低钠血症，同时伴有血清低渗透压和不适当的尿高渗透压和尿钠分泌，导致诊断为抗利尿激素不适当分泌综合征。低钠血症得到改善，该犬的临床状况得到改善，并在入院后 3 天出院。
这是第一例因创伤而患有抗利尿激素不适当分泌综合征的犬的病例描述。在兽医患者中，抗利尿激素不适当分泌在很大程度上未被认识。提高对该综合征的认识可以导致开始进行适当的治疗并改善结果。
