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在英国使用图像和性能增强药物的证据生成:英国合成代谢类固醇网络进行的范围审查和专家咨询的结果。

Generating evidence on the use of Image and performance enhancing drugs in the UK: results from a scoping review and expert consultation by the Anabolic Steroid UK network.

机构信息

Substance Use & Associated Behaviours, Department of Sociology, Manchester Metropolitan University, Manchester, UK.

Public Health Institute, Liverpool John Moores University, Liverpool, UK.

出版信息

Harm Reduct J. 2021 Oct 17;18(1):107. doi: 10.1186/s12954-021-00550-z.

DOI:10.1186/s12954-021-00550-z
PMID:34657627
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8522223/
Abstract

BACKGROUND

The use of anabolic androgenic steroids (AAS) and associated image and performance enhancing drugs (IPEDs) is now a global phenomenon. There is a need to develop evidence to support the development of interventions to prevent the commencement of use, to minimise the potential harms or to support those in their cessation of use. While the United Kingdom (UK) is no exception to this issue, its public health and legislative response to the phenomenon differs to other countries and requires the examination of research specific to the UK. Therefore, a scoping review has been conducted to examine the recent relevant literature to help inform the development and evaluation of effective interventions to reduce the harmful use of IPEDs.

METHODS

A comprehensive search strategy was developed for multiple bibliographic databases, supported by and iterative citation searching process and complimented by expert input from the Anabolic Steroid UK Network. Research conducted by or UK academics or within the UK were eligible, if published in the previous five years.

RESULTS

In total 87 eligible outputs were identified, including 26 review articles, 25 qualitative papers and 24 quantitative papers. together with small numbers of clinical studies/case reports (6) and commentaries/correspondence (6). The most common topics of research were public health, treatment and harm reduction (41), followed by studies focusing on epidemiology, sub-groups of people using IPEDs and motivations for use (34). The studies illustrated the diverse populations of people who use a range of enhancement drugs including concomitant psychoactive drug use. A number of papers focused on blood borne viruses and associated issues, while others reported on the uptake of needle and syringe programmes. No effectiveness evaluations related to any aspect of treatment, harm reduction or other intervention were published during study period.

CONCLUSION

There is a need for the development of effectiveness evaluations of current interventions and any future service provision for people using image and performance enhancing drugs. While there have been no studies of this nature to date, this review illustrates the rich data that has been gathered through diverse methodologies, that will assist in the development of future effectiveness evaluations.

摘要

背景

合成代谢雄激素类固醇(AAS)和相关的形象和性能增强药物(IPED)的使用现在是一个全球性的现象。需要开发证据来支持干预措施的发展,以防止开始使用,尽量减少潜在的危害,或支持那些停止使用。虽然英国(英国)也不例外,但它对这一现象的公共卫生和立法反应与其他国家不同,需要研究特定于英国的研究。因此,进行了范围审查,以审查最近的相关文献,以帮助为减少 IPED 有害使用的有效干预措施的制定和评估提供信息。

方法

为多个书目数据库制定了全面的搜索策略,得到了迭代引用搜索过程的支持,并得到了英国合成代谢类固醇网络专家的投入。研究由英国学者进行或在英国进行,如果在过去五年内发表,则符合条件。

结果

共确定了 87 项符合条件的产出,包括 26 篇综述文章、25 篇定性论文和 24 篇定量论文。以及少量的临床研究/病例报告(6)和评论/通信(6)。最常见的研究主题是公共卫生、治疗和减少危害(41),其次是关注流行病学、使用 IPED 亚组的人和使用动机的研究(34)。这些研究说明了使用一系列增强药物的人群的多样性,包括同时使用精神活性药物。一些论文侧重于血液传播病毒和相关问题,而另一些论文则报告了针具和注射器方案的采用情况。在研究期间,没有发表任何与治疗、减少危害或其他干预措施的任何方面相关的有效性评估。

结论

需要对目前的干预措施和任何未来为使用形象和性能增强药物的人提供的服务进行有效性评估。虽然迄今为止还没有此类研究,但本综述说明了通过各种方法收集的丰富数据,这将有助于未来有效性评估的发展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/7d124136981a/12954_2021_550_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/eb671da6dca6/12954_2021_550_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/41dfee17bd6c/12954_2021_550_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/7d124136981a/12954_2021_550_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/eb671da6dca6/12954_2021_550_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/41dfee17bd6c/12954_2021_550_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2cee/8522223/7d124136981a/12954_2021_550_Fig3_HTML.jpg

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