Medical Physics, CancerCare Manitoba, Canada R3E 0V9.
Med Phys. 2010 Jun;37(6):2525-32. doi: 10.1118/1.3425786.
The purpose of this work was to develop a quality assurance (QA) tool for high-dose-rate (HDR) brachytherapy that would quickly and easily verify both source positioning (dwell positions) and durations (dwell times).
The authors constructed a QA tool that combined radiochromic film to verify position with four photodiode detectors to verify dwell times. To characterize the temporal accuracy of the tool, a function generator powered four red light-emitting diodes that were optically coupled to the four photodiode detectors. The QA tool was used to verify the dwell positions and times of a commercial brachytherapy afterloader. Measurements of dwell time were independently verified by a one-dimensional optical camera that acquired 1000 lines/s.
The temporal accuracy of the QA tool was found to be about 1 ms. For visual assessment, the source position could be located within about 0.5 mm. Evaluating the accuracy and precision of an HDR brachytherapy afterloader, the authors found that the bias in dwell time can exceed 60 ms and the dwell time associated with the first dwell position had an unexpectedly large standard deviation of 30 ms. They found that the source locations were much easier to locate on the film if a plastic catheter was used instead of a metal treatment tube. Scanning the films enabled the dwell positions to be determined within about 0.2 mm.
For pretreatment QA, the authors found that this tool allowed verification of dwell positions and dwell times in about 6 min.
本研究旨在开发一种用于高剂量率(HDR)近距离放射治疗的质量保证(QA)工具,该工具能够快速、简便地验证源位置(驻留点位置)和持续时间(驻留时间)。
作者构建了一个 QA 工具,该工具结合了放射色胶片来验证位置,并用四个光电二极管探测器来验证驻留时间。为了表征该工具的时间准确性,作者使用函数发生器为四个红光发光二极管供电,这些发光二极管通过光纤与四个光电二极管探测器光学耦合。使用该 QA 工具验证了一种商业近距离放射治疗后装器的驻留点位置和时间。驻留时间的测量由一维光学相机独立验证,该相机以 1000 线/秒的速度采集数据。
发现 QA 工具的时间准确性约为 1 毫秒。对于目视评估,源位置可以定位在大约 0.5 毫米以内。评估 HDR 近距离放射治疗后装器的准确性和精密度时,作者发现驻留时间的偏差可能超过 60 毫秒,并且第一个驻留点的驻留时间具有出乎意料的大标准差 30 毫秒。他们发现,如果使用塑料导管而不是金属治疗管,胶片上更容易定位源位置。扫描胶片可以将驻留点位置确定在大约 0.2 毫米以内。
对于预处理 QA,作者发现该工具允许在大约 6 分钟内验证驻留点位置和驻留时间。