Mathew Amit, Rai Ekta
Department of Anaesthesia, Christian Medical College, Vellore, Tamil Nadu, India.
Saudi J Anaesth. 2021 Oct-Dec;15(4):435-440. doi: 10.4103/sja.sja_140_21. Epub 2021 Sep 2.
Appropriate fluid management is vital for adequate tissue perfusion and balancing the internal milieu especially in perioperative settings and critically ill children. Pediatric population is heterogeneous so one formula may not suffice and hence both the quantitative and qualitative perspective of fluid management should be based on physiology and pathology of the child along with their perioperative needs. In perioperative setup, the fluid is administered to meet fluid deficits (fasting, and other daily based losses), blood losses and third space losses. Anesthetists have always followed pediatric maintenance fluid calculations based on Holiday and Segar formula; based on studies conducted on healthy children more than 70 years ago. Recently, there has been a lot of debate about this concept, especially as there are serious concerns regarding the development of complications like hyponatremia and hyperglycemia, both of which can result in neurological damage or even mortality in a sick child. This review is an attempt to provide a historical perspective and current evidence-based approach to peri-operative pediatric fluid management. We performed a PUBMED search for articles using keywords including 'children', 'intravenous fluid therapy', 'crystalloids', 'colloids', 'fluid homeostasis', 'blood loss', 'estimation of blood loss', 'blood loss management', 'perioperative fluid ' to get our source articles.
适当的液体管理对于维持足够的组织灌注和平衡内环境至关重要,尤其是在围手术期和危重症儿童中。儿科人群具有异质性,因此单一的公式可能并不适用,所以液体管理的量和质的方面都应基于儿童的生理和病理状况以及他们的围手术期需求。在围手术期,给予液体以弥补液体缺失(禁食和其他每日损失)、失血和第三间隙损失。麻醉医生一直遵循基于霍利迪和西加尔公式的儿科维持液量计算方法;该公式是基于70多年前对健康儿童进行的研究得出的。最近,关于这一概念存在很多争议,尤其是因为人们严重担心低钠血症和高血糖等并发症的发生,这两种情况都可能导致患病儿童出现神经损伤甚至死亡。这篇综述旨在提供围手术期儿科液体管理的历史观点和当前基于证据的方法。我们在PubMed上使用关键词“儿童”、“静脉输液治疗”、“晶体液”、“胶体液”、“液体稳态”、“失血”、“失血估计”、“失血管理”、“围手术期液体”搜索文章以获取我们的源文章。